Table 3—

Adjusted odds ratio (OR) and 95% CI of prevalent metabolic syndrome by category of six BFRs (n = 637)*

AnalyteNot detectableDetectable
P trendP quadratic
<25th25th to <50th50th to <75th≥75th
PBB-153
    Median serum concentration (ng/g of lipid)1.22.33.813.1
    Cases/n18/8238/13765/14559/13757/136
    Adjusted OR (95% CI)Referent1.5 (0.7–3.2)3.1 (1.4–6.5)3.1 (1.4–6.7)3.1 (1.4–6.9)<0.010.07
PBDE-28
    Median serum concentration (ng/g of lipid)0.71.22.05.4
    Cases/n50/14241/14944/10750/11652/123
    Adjusted OR (95% CI)Referent0.8 (0.4–1.5)1.7 (0.9–3.1)1.5 (0.8–2.8)1.3 (0.7–2.4)0.090.49
PBDE-47
    Median serum concentration (ng/g of lipid)6.513.728.273.3
    Cases/n6/2064/17058/16155/14254/144
    Adjusted OR (95% CI)Referent1.1 (0.3–3.5)0.8 (0.3–2.8)1.2 (0.4–4.0)1.1 (0.3–3.6)0.700.72
PBDE-99
    Median serum concentration (ng/g of lipid)3.15.39.226.9
    Cases/n82/22350/12234/9937/8834/105
    Adjusted OR (95% CI)Referent1.1 (0.7–2.0)1.0 (0.6–1.8)1.9 (1.0–3.5)0.8 (0.5–1.5)0.750.24
PBDE-100
    Median serum concentration (ng/g of lipid)1.42.85.616.8
    Cases/n16/5267/16453/13647/14454/141
    Adjusted OR (95% CI)Referent1.8 (0.8–4.1)1.5 (0.6–3.4)1.6 (0.7–3.6)1.7 (0.7–3.8)0.680.61
PBDE-153
    Median serum concentration (ng/g of lipid)1.93.66.624.6
    Cases/n19/5265/16254/13352/14347/147
    Adjusted OR (95% CI)Referent2.1 (1.0–4.6)2.5 (1.1–5.6)2.4 (1.0–5.3)1.7 (0.7–3.8)0.690.02
  • * Adjusted for age, sex, race, poverty income ratio, BMI, cigarette smoking, serum cotinine, alcohol consumption, and exercise.

  • Displayed is the median serum concentration in each category.

  • P trend was calculated without a quadratic term in the model, while P quadratic was calculated including the linear term.