Table 1—

Anthropometric and biochemical characteristics of study subjects

Study subjectsAge- and sex-adjusted correlations between plasma IGF-1 levels and cardiometabolic variables
Age- and sex-adjusted correlations between plasma IL-6 levels and cardiometabolic variables
Pearson's correlation coefficient (r)PPearson's correlation coefficient (r)P
Sex (M/F)80/106
Age (years)41 ± 14−0.53*0.00010.30*0.0001
BMI (kg/m2)30.1 ± 8.4−0.280.00010.330.0001
Waist circumference (cm)97 ± 16−0.290.00010.350.0001
SBP (mmHg)127 ± 19−0.150.040.150.04
DBP (mmHg)80 ± 11−0.100.180.130.08
Total Cholesterol (mg/dl)198 ± 410.030.66−0.0060.95
HDL Cholesterol (mg/dl)54 ± 140.110.11−0.070.33
Triglyceride (mg/dl)121 ± 69−0.190.010.100.15
Fasting Glucose (mgl/dl)90 ± 140.030.63−0.0070.93
2-h glucose (mg/dl)117 ± 39−0.070.420.130.11
Fasting Insulin (μU/ml)12 ± 7−0.160.030.280.0001
IGF-1 (ng/ml)191 ± 90−0.150.04
IL-6 (pg/ml)2.5 ± 2.2−0.150.04
HOMA2.7 ± 1.8−0.210.0040.220.002
WBGD (mg · kg−1 · min−1)7.6 ± 3.20.290.002−0.350.0001
AHA-NHLB–defined metabolic syndrome (yes/no)60/126 (32.3)
High waist circumference (≥102 cm for men and ≥88 cm for women) (yes/no)91/95 (48.9)
High fasting glucose (≥100 mg/dl) (yes/no)47/139 (25.3)
High triglyceride (≥150 mg/dl l) (yes/no)50/136 (26.8)
Low HDL (<40 mg/dl in men or <50 mg/dl in women) (yes/no)54/132 (29.0)
High blood pressure (SBP ≥130 mmHg or DBP ≥85 mmHg) (yes/no)101/85 (54.6)
  • Data are means ± SD and n (%). Fasting plasma insulin, triglycerides, and IL-6 levels were log transformed for statistical analysis, but values in the table represent a back transformation to the original scale. DBP, diastolic blood pressure; SBP, systolic blood pressure.

  • * Adjusted for sex.