Table 1

Anthropometric and laboratory parameters of study subjects

Type 2 diabetesIGTNGT
n (female/male)99 (53/46)77 (42/35)187 (112/75)
Anthropometric parameters
    Age (years)63 ± 1163 ± 1260 ± 13
    Body weight (kg)77 ± 1771 ± 1677 ± 17
    Height (cm)161 ± 9158 ± 10160 ± 10
    BMI (kg/m2)30.0 ± 6.328.3 ± 5.029.9 ± 6.0
    Waist (cm)98 ± 1494 ± 1495 ± 15
    Waist-to-thigh ratio1.84 ± 0.19*1.81 ± 0.231.74 ± 0.24
    Smoking habit n (%)20 (20%)15 (19%)46 (25%)
    Alcohol consumption (alcohol units)3 ± 112 ± 102 ± 8
    Systolic blood pressure (mmHg)161 ± 24*155 ± 20151 ± 21
    Diastolic blood pressure (mmHg)86 ± 14*83 ± 1382 ± 12
Biochemical laboratory parameters
    Glucose (mmol/l)7.27 ± 1.67*5.55 ± 0.83*5.11 ± 0.50
    2-h glucose (mmol/l)12.71 ± 3.83*9.10 ± 0.83*4.83 ± 1.22
    Cholesterol (mmol/l)6.00 ± 1.036.03 ± 1.016.15 ± 1.24
    HDL cholesterol (mmol/l)1.14 ± 0.34*1.34 ± 0.491.32 ± 0.39
    Triglycerides (mmol/l)1.63 ± 0.92*1.37 ± 0.571.38 ± 0.51
    ALT (units/liter)27 ± 1028 ± 1126 ± 8
    AST (units/liter)24 ± 1123 ± 1522 ± 15
    GGT (units/liter)36 ± 3035 ± 3127 ± 30
    ALP (units/liter)174 ± 51176 ± 45172 ± 45
    Fibrinogen (mg/dl)286 ± 79297 ± 66275 ± 61
Hormones
    Insulin (pmol/l)131 ± 108*103 ± 5295 ± 41
    Leptin (ng/ml)10.7 ± 4.510.0 ± 5.810.4 ± 5.0
    MCP-1/CCL2 (pg/ml)224 ± 275*195 ± 171159 ± 113
Insulin sensitivity
    QUICKI0.127 ± 0.014*0.136 ± 0.0140.138 ± 0.011
  • Data are means ± SD or n (%). Leptin, insulin, triglycerides, glucose, AST, ALT, GGT, and ALP are expressed as geometric means ±SD. Subjects with a previously proved diagnosis of diabetes did not undergo an OGTT.

  • *P < 0.05 vs. NGT.

  • P < 0.05 vs. IGT ANOVA and Bonferroni post hoc analysis.