Table 2

Baseline distributions and 4-, 5-, and 10-year rates for PDF and SVL by time periods

1975–1985
1986–2008
κn/NMeta-analyzed (%)Mean (95%CI)κn/NMeta-analyzed (%)Mean (95%CI)
Baseline distributions, 4 years
    GHb (%)12,36611.7 (10.2–13.2)47958.4 (7.3–9.5)
    Systolic blood pressure (mmHg)12,366136.0 (114.4–157.6)3760139.2 (127.4–151.1)
    Diastolic blood pressure (mmHg)12,36679.0 (78.6–79.5)260078.8 (73.1–84.5)
    Retinopathy level (%)
        No retinopathy21,447/3,31943.66882/1,32466.6
        NPDR41,693/3,60447.06271/1,32420.5
        PDR4460/3,60412.8642/1,3243.2
    Presence of DME (%)2602/195330.8378/77510.1
5-year incidence 4-year incidence
    PDR (%)4353/3,21419.5 (2.4–36.6)*526/1,1382.6 (0.2–5.0)*
    SVL (%)3320/2,9679.7 (0.0–21.9)*28/3043.2 (0.0–9.2)*
Baseline distributions, 5 years
    GHb (%)37,2959.3 (7.8–10.7)22,2458.0 (7.9–8.1)
    Systolic blood pressure (mmHg)1133150.0 (146.9–153.1)2171136.1 (121.2–151.0)
    Diastolic blood pressure (mmHg)113393.0 (91.3–94.7)217181.1 (78.1–84.1)
    Retinopathy level (%)
        No retinopathy53,521/7,49147.061,731/2,65165.3
        NPDR63,387/7,70244.06762/2,65128.7
        PDR6787/7,70210.26138/2,6515.2
Presence of DME (%)33,134/5,66455.34222/2,5168.8
5-year incidence
    PDR (%)61,046/5,15318.0 (3.5–32.5)*678/20516.4 (0.4, 12.4)*
    SVL (%)4689/7,59513.7 (0.9–26.5)*214/1,8733.60 (0.0, 11.4)*
Baseline distributions, 10 years
    GHb (%)49,7779.3 (7.6–10.9)37968.2 (7.7–8.7)
    Systolic blood pressure (mmHg)59,910139.0 (129.3–148.7)2684138.3 (127.3–149.2)
    Diastolic blood pressure (mmHg)59,91083.8 (78.6, 88.9)268481.5 (78.2, 84.8)]
    Retinopathy level (%)
        No retinopathy65,733/9,93957.73526/79666.1
        NPDR53,280/9,91033.13141/79617.7
        PDR4732/5,98112.220/4080.0
    Presence of DME (%)10/290.030/7960.0
10-year incidence
    PDR (%)3357/1,72911.5 (0.0–25.7)*217/4006.6 (0.0, 18.3)*
    SVL (%)4232/9,2056.0 (0.9–11.1)*211/4842.6 (0.0–7.1)*
  • Data are κ (number of studies), n (total number of patients at risk at each time point), percent, or mean (95% CI).

  • *Heterogeneity by Cochran Q: P < 0.05. DME, diabetic macular edema.