Table 1—

Baseline characteristics and changes after 12 months in the Bright Bodies and control groups

Baseline
Change after 12 months
Treatment effect*P
Bright BodiesControlPBright BodiesControl
n13101310
IFG/IGT3 (23)1 (10)0.370 (0)5 (50)0.50 (0.09–0.80)0.007*
Age (years)11.312.1
Sex (male)4 (31)5 (50)
Race/ethnicity
    White4 (31)5 (50)
    Black5 (38)3 (30)
    Hispanic4 (31)2 (20)
Height (cm)150.79 ± 2.10160.36 ± 3.410.2564.02 ± 0.755.06 ± 0.63−1.04 (−3.2 to 1.1)0.323
Weight (kg)78.78 ± 7.0189.96 ± 5.990.8364.18 ± 1.8511.56 ± 1.12−7.38 (−12.6 to −2.9)0.031*
BMI (kg/m2)34.08 ± 2.2934.70 ± 1.720.6980.15 ± 0.672.15 ± 0.45−2.00 (−4.0 to −0.4)0.017*
BMI (z score)2.40 ± 0.12.50 ± 0.080.387−0.11 ± 0.060.06 ± 0.03−0.17 (−0.3 to −0.01)0.034*
Body fat (%)45.95 ± 2.2743.79 ± 2.520.101−1.82 ± 1.47.17 ± 1.6−8.99 (−13.6 to −4.3)<0.001*
Lean body mass (kg)42.42 ± 2.8255.79 ± 3.350.7554.62 ± 2.1−1.24 ± 1.795.86 (−0.7 to 13.4)0.076
Fat mass (kg)35.53 ± 5.4943.48 ± 3.130.023−0.07 ± 1.2613.05 ± 1.15−13.12 (−17.1 to −9.2)<0.001*
Fasting glucose (mg/dl)91.8 ± 1.3591.0 ± 2.330.734−1.04 ± 0.892.6 ± 2.07−3.64 (−7.9 to 0.7)0.090
Glucose120 (mg/dl)116.3 ± 5.73113.3 ± 6.320.179−5.54 ± 5.989.1 ± 5.82−14.64 (−32.4 to 3.1)0.100
AUCglucose (mg/dl)121.6 ± 4.81121.9 ± 6.150.754−5.38 ± 4.276.61 ± 2.98−11.99 (−23.5 to 5.5)0.042*
Fasting insulin (μU/ml)‖§30.0 (9.7)34.0 (19.2)0.960−4.5 (8.55)3.0 (8.8)−7.50 (−17.0 to 2.0)0.070
AUCinsulin (μU/ml)‖§147.1 (111.5)102.1 (87.6)0.290−50.9 (84.57)47.0 (63.9)−97.9 (−161.5 to −34.3)0.003*
WBISI§1.51 (0.80)2.42 (0.70)0.5000.63 (0.70)−0.07 (0.58)0.70 (0.04–1.56)0.007*
  • Data are n, n (%), or means ± SEM of a paired t test unless otherwise indicated.

  • * Treatment effect: difference in change in the Bright Bodies and control groups (95% CI).

  • P value based on Fisher's exact test.

  • Difference in proportions (95% CI) (ref. 7).

  • § Wilcoxon's rank-sum test median (interquartile range) (ref. 8). IFG, impaired fasting glucose; IGT, impaired glucose tolerance; WBISI, whole body insulin sensitivity index.