Adjusted odds ratios and 95% CIs for the effect of clinical variables on the risk of orthostatic hypotension in subjects with NGT, pre-diabetes, and diabetes based on multiple logistic regression analysis
| NGT | Pre-diabetes | Diabetes | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Odds ratio (95% CI) | P value | Odds ratio (95% CI) | P value | Odds ratio (95% CI) | P value | ||||
| n | 1,069 | 412 | 157 | ||||||
| Age (years) | 1.023 (1.008–1.130) | 0.030 | 1.058 (1.005–1.114) | 0.031 | 1.012 (0.996–1.028) | 0.130 | |||
| Sex, male vs. female | 1.295 (0.858–1.956) | 0.219 | 1.081 (0.612–1.912) | 0.788 | 1.431 (0.568–3.605) | 0.448 | |||
| A1C (%) | 1.105 (0.810–1.479) | 0.491 | 1.166 (0.735–1.850) | 0.514 | 1.269 (1.010–1.598) | 0.028 | |||
| Hypertension, yes vs. no | 2.079 (1.106–4.194) | 0.024 | 2.330 (1.130–4.455) | 0.020 | 3.190 (1.187–6.953) | 0.018 | |||
| Antihypertensive use, yes vs, no | 0.682 (0.259–1.792) | 0.437 | 0.960 (0.372–2.479) | 0.933 | 0.782 (0.235–2.601) | 0.689 | |||
| 30 max–to–15 min ratio | 0.123 (0.141–0.910) | 0.036 | 0.119 (0.006–2.503) | 0.171 | 0.358 (0.064–1.995) | 0.241 | |||
Dependent variable: orthostatic hypotension; independent variables: age, sex, BMI, physical activity, A1C, hypertension, cerebrovascular disease, ischemic ECG pattern, 30 max–to–15 min ratio, and antihypertensive use.