Table 2—

Baseline characteristics and multivariate adjusted HR (95% CI) for death from stroke for subjects according to FPG and 2-h plasma glucose categories

FPG
2-h plasma glucose
Known diabetes
<6.16.1–6.9≥7.0<7.87.8–11.0≥11.1
Men
    n (%)8,540 (72.1)2,043 (17.2)537 (4.5)9,065 (76.5)1,558 (13.2)497 (4.2)724 (6.1)
    Age (years)56.9 ± 0.157.2 ± 0.362.4 ± 0.555.8 ± 0.163.2 ± 0.365.1 ± 0.562.8 ± 0.4
    BMI (kg/m2)26.3 ± 0.027.4 ± 0.129.0 ± 0.226.3 ± 0.027.7 ± 0.128.9 ± 0.228.3 ± 0.1
    Cholesterol (mmol/l)6.04 ± 0.016.09 ± 0.036.11 ± 0.056.07 ± 0.015.99 ± 0.036.04 ± 0.055.78 ± 0.04
    SBP (mmHg)140 ± 0.2145 ± 0.4148 ± 0.9140 ± 0.2147 ± 0.5151 ± 0.9145 ± 0.7
    DBP (mmHg)83 ± 0.185 ± 0.387 ± 0.583 ± 0.186 ± 0.387 ± 0.584 ± 0.4
    Smoking2,507 (29.4)637 (31.2)157 (29.2)2,835 (31.3)360 (23.1)106 (21.3)166 (22.9)
    Stroke
n (%)141 (1.7)45 (2.2)15 (2.8)153 (1.7)35 (2.2)13 (2.6)30 (4.1)
n per 1,000 person-years1.461.903.241.432.473.505.57
HR (95% CI)11.05 (0.74–1.49)1.37 (0.79–2.38)11.43 (0.97–2.11)1.82 (1.01–3.29)3.32 (2.16–5.12)
Women
    n (%)8,169 (82.8)969 (9.8)252 (2.6)7,766 (78.7)1,281 (13.0)343 (3.5)472 (4.8)
    Age (years)54.9 ± 0.159.0 ± 0.361.1 ± 0.654.5 ± 0.159.6 ± 0.362.4 ± 0.560.8 ± 0.5
    BMI (kg/m2)26.5 ± 0.128.6 ± 0.230.6 ± 0.326.4 ± 0.128.6 ± 0.130.0 ± 0.330.1 ± 0.2
    Cholesterol (mmol/l)6.22 ± 0.016.27 ± 0.046.32 ± 0.076.22 ± 0.016.27 ± 0.036.21 ± 0.065.86 ± 0.05
    SBP (mmHg)137 ± 0.2141 ± 0.7143 ± 1.3137 ± 0.2144 ± 0.6147 ± 1.1147 ± 1.0
    DBP (mmHg)80 ± 0.181 ± 0.482 ± 0.780 ± 0.183 ± 0.384 ± 0.681 ± 0.5
    Smoking1,650 (20.2)237 (24.5)67 (26.6)1,712 (22.0)184 (14.4)58 (16.9)67 (14.2)
    Stroke
n (%)37 (0.5)10 (1.0)7 (2.8)36 (0.5)9 (0.7)9 (2.6)14 (3.0)
n per 1,000 person-years0.441.253.350.460.723.033.93
HR (95% CI)12.04 (0.99–4.21)4.73 (2.00–11.18)10.90 (0.43–1.90)3.33 (1.55–7.14)5.60 (2.86–10.96)
Total
    n (%)16,709 (77.0)3,012 (13.9)789 (3.6)16,831 (77.5)2,839 (13.1)840 (3.9)1,196 (5.5)
    Age (years)56.0 ± 0.157.6 ± 0.261.8 ± 0.455.2 ± 0.161.6 ± 0.263.9 ± 0.461.9 ± 0.3
    BMI (kg/m2)26.4 ± 0.027.9 ± 0.129.5 ± 0.126.4 ± 0.028.1 ± 0.129.3 ± 0.129.1 ± 0.1
    Cholesterol (mmol/l)6.12 ± 0.016.20 ± 0.026.20 ± 0.046.14 ± 0.016.11 ± 0.026.12 ± 0.045.83 ± 0.03
    SBP (mmHg)139 ± 0.2144 ± 0.4146 ± 0.7138 ± 0.2145 ± 0.4149 ± 0.7146 ± 0.6
    DBP (mmHg)82 ± 0.183 ± 0.285 ± 0.482 ± 0.185 ± 0.286 ± 0.482 ± 0.3
    Smoking4,157 (24.9)874 (29.0)224 (28.4)4547 (27)544 (19.2)164 (19.5)233 (19.5)
    Stroke
n (%)178 (1.1)55 (1.8)22 (2.8)189 (1.1)44 (1.5)22 (2.6)44 (3.7)
n per 1,000 person-years0.981.743.271.021.653.294.92
HR (95% CI)11.19 (0.87–1.64)1.83 (1.16–2.89)11.30 (0.92–1.84)2.31 (1.46–3.67)3.85 (2.68–5.53)
  • Data are n (%) and means ± SE unless otherwise indicated. Data are adjusted for age, study, and sex (when men and women combined). FPG and 2-h plasma glucose criteria are in mmol/l. DBP, diastolic blood pressure; SBP, systolic blood pressure.