Table 2—

Comparison of pharmacodynamic parameters for subjects using aspart and lispro

Pharmacodynamic parametersDay 1
PDay 4
P
AspartLisproDifference (95% CI)AspartLisproDifference (95% CI)
AUCGIR (mg/kg)982 ± 83919 ± 17563 (−341 to 467)0.76839 ± 124854 ± 11615 (−354 to 325)0.93
GIRmax (mg · kg−1 · min−1)7.3 ± 0.66.4 ± 1.10.96 (−1.57 to 3.49)0.467.7 ± 0.97.3 ± 1.00.39 (−2.38 to 3.16)0.78
TmaxGIR (min)101 ± 992 ± 119 (−19 to 37)0.5379 ± 979 ± 70.14 (−23 to 22)0.99
Time to discontinuation of exogenous glucose (min)263 ± 10246 ± 1516 (−21 to 54)0.40208 ± 20214 ± 176 (−58 to 45)0.81
Ti50 (min)58 ± 646 ± 512 (−3 to 27)0.1438 ± 439 ± 41 (−12 to 9)0.79
Td50 (min)199 ± 13191 ± 128 (−27 to 42)0.66136 ± 10168 ± 1332 (−64 to 0.58)0.07
  • Data are means ± SE unless indicated otherwise.