Table 1—

Estimates of the indexes computed by the oral and the intravenous mathematical models

Control subjectsDiabetic subjects before BPDDiabetic subjects after BPD
Indexes OGTT
    SI × 102 (ml · min−1 · kgFFM−1 · pmol−1 · l)2.70 ± 0.980.64 ± 0.193.60 ± 0.97*
    SI post/SI pre6.3 ± 3.1
    Φd × 10−9500 ± 140203 ± 144480 ± 365
    Φs × 10−9 (min−1)39.2 ± 20.823.0 ± 10.032.0 ± 16.0
    Φ × 10−9 (min−1)47.7 ± 24.325.9 ± 11.237.7 ± 12.0#
    AUCISR (nmol · m−2)33.4 ± 12.862.3 ± 28.437.2 ± 13.3
    DI × 10−14 (dl · min−2 · kgFFM−1 · pmol−1 · l)1,197 ± 599148 ± 511,227 ± 276
Indexes IVGTT
    SI × 102 (ml · min−1 · kgFFM−1 · pmol−1 · l)2.10 ± 0.801.04 ± 0.282.70 ± 0.60§
    SI post /SI pre2.7 ± 1.1
    Φ1 × 10−9242 ± 19927.9 ± 17.1164 ± 119§
    Φ2 × 10−9 (min−1)10.2 ± 2.910.0 ± 4.812.5 ± 8.5
    Φ × 10−9 (min−1)16.6 ± 5.310.8 ± 5.216.5 ± 9.5#
    AUCISR (nmol · m−2)23.9 ± 3.743.9 ± 22.841.9 ± 21.7
    DI × 10−14 (dl · min−2 · kgFFM−1 · pmol−1 · l)341 ± 124118 ± 78453 ± 318§
Indexes EHC
    SI × 102 (ml · min−1 · kgFFM−1 · pmol−1 · l)1.4 ± 0.74.5 ± 1.5
    SI post /SI pre3.5 ± 1.2
  • Data are means ± SD. OGTT (after/before):

  • *

    * P < 0.005;

  • #

    # P < 0.05;

  • P < 0.02. Diabetic subjects after BPD/control subjects: NS. IVGTT (after/before):

  • §

    § P < 0.01;

  • #P < 0.05. Diabetic subjects after BPD/control subjects: NS. EHC: SI before BPD is significantly different from SI (OGTT) (P < 0.001). SI (OGTT) and SI (IVGTT) before BPD are significantly different (P < 0.05); SI (EHC), SI (OGTT), and SI (IVGTT) after BPD are not significantly different.