Table 1—

Baseline characteristics of the intent to treat study population by treatment group

VariablePRANDIALBASALP value
n557558
Sex0.680
    Female201 (36.1)208 (37.3)
    Male356 (63.9)350 (62.7)
Age (years)
    Mean61.1 ± 9.760.9 ± 9.80.724
    Aged ≥65202 (36.3)220 (39.4)0.277
Origin0.302
    Caucasian484 (86.9)483 (86.6)
    Western Asian61 (11.0)58 (10.4)
    African descent1 (0.2)6 (1.1)
    Other11 (2.0)11 (2.0)
Country>0.999
Duration of diabetes (years)9.3 ± 7.29.0 ± 7.30.518
Current tobacco use*93 (16.7)81 (14.5)0.316
Past tobacco use (years)*13.7 ± 16.512.3 ± 15.40.143
Weight (kg)81.12 ± 15.1781.86 ± 15.860.513
BMI (kg/m2)29.0 ± 4.629.2 ± 5.00.380
Overweight (BMI ≥25 kg/m2)449 (80.8)447 (80.3)0.832
Systolic blood pressure (mmHg)126.88 ± 16.63127.76 ± 17.750.346
Diastolic blood pressure (mmHg)76.60 ± 9.0676.87 ± 9.560.542
Prior myocardial infarction*99 (17.8)101 (18.1)0.858
Thrombolysis (recent AMI)*97 (17.4)98 (17.6)0.970
Intravenous insulin infusion (recent AMI)160 (28.8)160 (28.8)0.807
A1C (%)8.42 ± 1.408.27 ± 1.520.089
Triglycerides (mmol/l)1.89 ± 1.151.77 ± 0.950.074
Total cholesterol (mmol/l)4.45 ± 1.254.45 ± 1.250.871
HDL cholesterol (mmol/l)0.96 ± 0.250.96 ± 0.230.607
LDL cholesterol (mmol/l)2.68 ± 1.022.71 ± 1.020.556
Urinary albumin-to-creatinine ratio (mg/g)115 ± 430163 ± 6100.171
QTc interval (ms)435 ± 33434 ± 340.428
LVEF (%)50.54 ± 10.0550.97 ± 10.080.829
  • Data are mean ± SD or n (%).

  • *

    * Unknown <1.5%.