Table 1

Baseline demographic, clinical, and laboratory characteristics by treatment group

OverallPlaceboMetforminLifestyleP
n3,2341,0821,0731,079
Age (years)50.6 ± 10.750.3 ± 10.450.9 ± 10.350.6 ± 11.30.45
Sex0.35
    Male1,043 (32.3)335 (31.0)363 (33.8)345 (32.0)
    Female2,191 (67.7)747 (69.0)710 (66.2)734 (68.0)
Race/ethnicity0.49
    Caucasian1,768 (54.7)586 (54.2)602 (56.1)580 (53.8)
    African American645 (19.9)220 (20.3)221 (20.6)204 (18.9)
    Hispanic508 (15.7)168 (15.5)162 (15.1)178 (16.5)
    American Indian171 (5.3)59 (5.5)52 (4.8)60 (5.6)
    Asian American142 (4.4)49 (4.5)36 (3.4)57 (5.3)
Fasting glucose (mmol/l)5.9 ± 0.55.9 ± 0.55.9 ± 0.55.9 ± 0.40.45
    2 h glucose (mmol/l)9.1 ± 0.99.1 ± 1.09.2 ± 1.09.1 ± 0.90.56
A1C (%)5.9 ± 0.505.9 ± 0.55.9 ± 0.55.9 ± 0.51.00
SBP (mmHg)123.7 ± 14.7123.5 ± 14.4124.0 ± 14.9123.7 ± 14.80.66
DBP (mmHg)78.3 ± 9.378.0 ± 9.278.3 ± 9.578.6 ± 9.20.33
Triglycerides (mmol/l)1.85 ± 1.081.91 ± 1.131.79 ± 1.021.84 ± 1.100.05
Total cholesterol (mmol/l)5.26 ± 0.945.25 ± 0.955.25 ± 0.925.28 ± 0.950.67
LDL cholesterol (mmol/l)3.23 ± 0.853.21 ± 0.873.23 ± 0.843.24 ± 0.850.76
HDL cholesterol (mmol/l)1.18 ± 0.311.16 ± 0.301.19 ± 0.301.19 ± 0.320.01
LDL size (Rf × 1,000)264.4 ± 29.6262.7 ± 31.1265.6 ± 28.7264.8 ± 29.00.06
  • Data are n (%) or means ± SD. RF, relative flotation.