Table 2

Incidence of acute pancreatitis associated with type 2 diabetes stratified by age and sex from a retrospective claims database study, 2000–2005

Nondiabetic cohort
Type 2 diabetic cohort
IRR: type 2 diabetic cohort vs. nondiabetic cohort (95% CI)
n*Incident casesPerson-years of follow-upIncidence rate per 100,000 person-years (95% CI)nIncident casesPerson-years of follow-upIncidence rate per 100,000 person-years (95% CI)
Overall age336,410827553,959.28149.29 (139.11–159.46)334,9302,551604,684.35421.87 (405.50–438.24)2.83 (2.61–3.06)
    18–30 years13,628917,029.6252.85 (18.32–87.38)13,5538119,780.12409.50 (320.32–498.68)7.75 (3.89–15.43)
    31–44 years78,518105120,783.1086.93 (70.30–103.56)78,051584132,996.11439.11 (403.50–474.72)5.05 (4.10–6.22)
    45–54 years120,354272200,359.38135.76 (119.62–151.89)119,823862217,352.86396.59 (370.11–423.07)2.92 (2.55–3.35)
    55–64 years91,859273154,084.70177.18 (156.16–198.19)91,526723167,069.73432.75 (401.21–464.30)2.44 (2.13–2.81)
    ≥65 years32,05116861,702.48272.27 (231.10–313.45)31,97730167,485.52446.02 (395.63–496.41)1.64 (1.36–1.98)
Sex
    Female148,868370242,728.54152.43 (136.90–167.97)148,2881058267,658.93395.28 (371.46–419.10)2.59 (2.30–2.92)
    Male187,542457311,230.74146.84 (133.37–160.30)186,6421493337,025.42442.99 (420.52–465.46)3.02 (2.72–3.35)
  • *Patients with events of acute pancreatitis (n = 594 from the nondiabetic cohort and n = 1,883 from the type 2 diabetic cohort) or chronic pancreatitis (n = 162 from the nondiabetic cohort and n = 656 from the type 2 diabetic cohort) during the 1-year baseline period were excluded from the numerator and the denominator. In addition, patients with chronic pancreatitis during follow-up were excluded (n = 26 from the nondiabetic cohort and n = 161 from the type 2 diabetic cohort). Note that some patients may have had more than one exclusionary event.