Table 2

Glucose tolerance, insulin sensitivity, and release

Normal-weight blackNormal-weight whiteObese blackObese white
n13141614
FSIGT
    SI (× 10−5 min−1/[pmol/l])4.4 ± 0.8*9.4 ± 0.8*2.9 ± 0.8§6.0 ± 0.8§
    AIRg (pmol/l)171.3 ± 42.5**58.6 ± 41.0**328.0 ± 38.2§78.2 ± 41.0§
    Disposition index (× 10−5 min−1)3,811 ± 5382,966 ± 5183,646 ± 4852,353 ± 518
    Sg (× 10−1 min)0.25 ± 0.030.24 ± 0.020.28 ± 0.020.24 ± 0.02
    Kg (%/min)2.81 ± 0.352.44 ± 0.343.46 ± 0.31*2.22 ± 0.34*
OGTT
    Fasting glucose (mmol/l)4.5 ± 0.14.4 ± 0.14.6 ± 0.14.7 ± 0.1
    Fasting insulin (pmol/l)59.0 ± 8.0*28.5 ± 7.7*§90.6 ± 7.252.5 ± 7.7§
    Δinsulin(0–30)/Δglucose(0–30)437 ± 70*184 ± 65*507 ± 65248 ± 65
    DIo (mmol/l)7.7 ± 1.37.6 ± 1.25.1 ± 1.25.0 ± 1.2
  • Values are unadjusted means ± SEM. All P values were adjusted for age.

  • *,†,‡,§Matching superscript symbols represent groups that are significantly different from each other, P < 0.05;

  • **P < 0.01.