Table 2

Sex differences in inflammatory markers, BMI, VAT, SAT, and TAT in type 2 diabetes

MenWomenP*
CRP (mg/l)2.3 (1.3–4.3)3.6 (1.6–9.7)<0.0001
ICAM-1 (ng/ml)243 (202–294)234 (179–301)0.7
MCP (pg/ml)62 (44–89)60 (43–87)0.8
VCAM-1 (mg/dl)682 (545–834)656 (525–807)0.07
Fibrinogen (mg/dl)306 (245–375)357 (276–421)<0.0001
MMP9 (ng/ml)451 (318–658)392 (298–559)0.4
PAI-1 (ng/ml)28 (20–43)30 (21–44)0.1
IL-6 (pg/ml)2.4 (1.8–3.6)2.5 (1.8–4.1)0.9
BMI (kg/m2)31.8 (28.4–35.2)32.7 (28.6–38.4)0.2
VAT (cm3)137 (105–180)103 (80–131)<0.0001
SAT (cm3)175 (128–220)220 (165–276)<0.0001
TAT (cm3)311 (245–395)328 (249–397)0.9
  • Data are medians (interquartile range 25th–75th percentiles).

  • *ANCOVA for comparison between sexes adjusted for age, BMI, diabetes therapy, duration of diabetes, years of smoking, statin use, and A1C.