Table 2

Metabolic control and attainment of treatment goals in type 2 diabetic patients with renal insufficiency randomly assigned to either usual or structured care for 2 years

Structured careUsual careP*
Completed 2 years of follow-up (%)81820.55
Systolic blood pressure (mmHg)
    Baseline145 ± 24144 ± 260.15
    Last available135 ± 25137 ± 210.15
Diastolic blood pressure (mmHg)
    Baseline74 ± 1274 ± 100.93
    Last available68 ± 1271 ± 120.02
A1C (%)
    Baseline8.2 ± 1.98.4 ± 0.20.62
    Last available7.3 ± 1.38.0 ± 1.6<0.01
Plasma triglycerides (mmol/l)
    Baseline2.3 ± 1.72.5 ± 2.20.61
    Last available1.8 ± 1.31.9 ± 1.10.06
HDL cholesterol (mmol/l)
    Baseline1.2 ± 0.31.2 ± 0.30.84
    Last available1.2 ± 0.41.2 ± 0.30.45
LDL cholesterol (mmol/l)
    Baseline3.1 ± 1.13.0 ± 1.00.60
    Last available2.49 ± 0.812.84 ± 1.10.14
Serum creatinine (μmol/l)
    Baseline196.3 ± 3.5198.8 ± 48.70.68
    Last available281.9 ± 134.7290.3 ± 28.70.37
Estimated glomerular filtration rate (ml/min per 1.73m2)
    Baseline31.4 ± 8.1431.3 ± 8.20.96
    Last available24.0 ± 10.226.6 ± 12.40.11
Use of ACE inhibitors or ARBs (%)
    Baseline7756<0.01
    Last visit6949<0.01
Use of insulin (%)
    Baseline61580.75
    Last visit65710.29
Patients attaining number of targets at last review visit (%)
    029
    11319
    22445
    32916
    4229
    5103
Attained at least 3 treatment goals (%)6128<0.01
% of patients attaining treatment target at last review visit
    Blood pressure <130/80 mmHg4927<0.01
    LDL cholesterol <2.6 mmol/l56410.02
    Triglycerides <2.0 mmol/l63470.24
    A1C <7%39260.19
  • Data are means ± SD or %.

  • *After adjustment for age, sex, and study centers.