Table 2

Cytokines and inflammatory factors in maternal and umbilical cord plasma at birth

Lean mothersObese mothersPAdjusted P value
n5368
Maternal
    leptin (ng/ml)31.9 ± 20.072.1 ± 34.70.00010.0001
    adiponectin (μg/ml)10.7 ± 4.69.7 ± 4.00.300.39
    TNF-α (pg/ml)1.4 ± 0.91.3 ± 0.50.670.56
    IL-6 (pg/ml)2.4 ± 1.44.6 ± 3.40.00010.0003
    CRP (ng/ml)8074 ± 646712433 ± 79180.0040.01
Umbilical cord
    leptin (ng/ml)8.2 ± 4.714.7 ± 13.60.0010.0001
    adiponectin (μg/ml)30.8 ± 10.030.6 ± 9.70.940.71
    TNF-α (pg/ml)1.7 ± 0.61.7 ± 0.30.900.67
    IL-6 (pg/ml)2.4 ± 1.43.5 ± 2.30.020.01
    CRP (ng/ml)121 ± 97202 ± 2860.250.30
  • Data are means ± SD. Maternal blood was obtained after an overnight fast at the time of admission for elective cesarean section. Umbilical blood was sampled from the clamped cord within 5 min of placental delivery. Maternal comparisons were adjusted for race, medical problems, and smoking. Neonatal and umbilical cord measurements were adjusted for race, medical problems, smoking, and sex.