Table 3

Relationship between year 15 oxidative stress markers and year 20 HOMA-IR

F2Isop
oxLDL
β-Coefficient ± SEPβ-Coefficient ± SEP
Model 1*0.0244 ± 0.01580.10.0727 ± 0.02080.0005
Model 20.0294 ± 0.01590.060.0753 ± 0.02080.0003
Model 3
BMI (kg/m2)−0.0192 ± 0.01650.20.0598 ± 0.02060.004
Waist circumference (cm)−0.0237 ± 0.01610.10.0432 ± 0.02060.04
Estimated body fat (%)−0.0217 ± 0.01630.20.0501 ± 0.02060.02
  • β-Coefficient is a change in HOMA-IR [ln (mU · l−1 · mmol−1 · l−1)] per one-unit increment of independent variables [ln(F2Isop) (ng/l) or ln(oxLDL) (units/l)].

  • *Model 1: adjusting for age, sex, race, study center, and year 15 HOMA-IR.

  • †Model 2: model 1 plus year 15 smoking status, physical activity, alcohol consumption, and education.

  • ‡Model 3: model 2 plus year 15 body fat measurements (BMI, waist circumference, or estimated percent body fat; adding each variable separately).