Table 1

Clinical and biochemical characteristics of subjects by TRIB3 Q84R genotype in MetS group

QQ84 (n = 125)QR84 (n = 79)RR84 (n = 13)P
P*
vs. QQ84 groupvs. QR84 groupvs. QQ84 groupvs. QR84 group
Sex (male/female)51/7439/409/40.0760.237
Age (years)55.15 ± 9.1454.71 ± 9.8456.85 ± 6.400.5320.442
BMI (kg/m2)28.95 ± 4.3128.80 ± 3.9029.61 ± 2.800.5810.508
Systolic blood pressure (mmHg)152.19 ± 22.11148.10 ± 20.72156.85 ± 28.470.4710.187
Diastolic blood pressure (mmHg)94.14 ± 14.0093.35 ± 13.7491.62 ± 16.050.5390.681
Waist circumference (cm)98.01 ± 9.7397.37 ± 10.42101.31 ± 8.810.2590.188
Waist-to-hip ratio0.93 ± 0.060.93 ± 0.060.96 ± 0.040.0410.041
Total cholesterol (mmol/l)5.29 ± 1.295.48 ± 1.106.03 ± 0.870.0380.1300.0560.198
Triglycerides (mmol/l)2.04 ± 0.922.57 ± 1.642.77 ± 1.240.0470.5870.0080.847
HDL cholesterol (mmol/l)1.25 ± 0.301.24 ± 0.421.04 ± 0.190.0340.0470.0770.063
LDL cholesterol (mmol/l)3.49 ± 0.943.58 ± 0.964.06 ± 1.070.0440.0980.0330.088
Fasting blood glucose (mmol/l)6.69 ± 2.416.64 ± 2.716.13 ± 2.470.4460.501
Insulin (μU/ml)20.47 ± 10.7620.04 ± 9.6719.23 ± 14.680.6940.802
HOMA-IR6.30 ± 4.715.84 ± 3.225.24 ± 4.500.3890.639
Normal IMT804120.0010.017
Mean IMT (mm)0.75 ± 0.150.76 ± 0.180.95 ± 0.180.000070.0002
Maximum IMT (mm)1.07 ± 0.691.23 ± 0.882.44 ± 1.170.000000050.000002
  • Data are means ± SD unless otherwise indicated.

  • *P, adjusted for waist-to-hip ratio, sex, age, and smoking. HOMA-IR, homeostasis model assessment for insulin resistance.