Clinical and biochemical characteristics of subjects by TRIB3 Q84R genotype in MetS group
| QQ84 (n = 125) | QR84 (n = 79) | RR84 (n = 13) | P | P* | |||
|---|---|---|---|---|---|---|---|
| vs. QQ84 group | vs. QR84 group | vs. QQ84 group | vs. QR84 group | ||||
| Sex (male/female) | 51/74 | 39/40 | 9/4 | 0.076 | 0.237 | ||
| Age (years) | 55.15 ± 9.14 | 54.71 ± 9.84 | 56.85 ± 6.40 | 0.532 | 0.442 | ||
| BMI (kg/m2) | 28.95 ± 4.31 | 28.80 ± 3.90 | 29.61 ± 2.80 | 0.581 | 0.508 | ||
| Systolic blood pressure (mmHg) | 152.19 ± 22.11 | 148.10 ± 20.72 | 156.85 ± 28.47 | 0.471 | 0.187 | ||
| Diastolic blood pressure (mmHg) | 94.14 ± 14.00 | 93.35 ± 13.74 | 91.62 ± 16.05 | 0.539 | 0.681 | ||
| Waist circumference (cm) | 98.01 ± 9.73 | 97.37 ± 10.42 | 101.31 ± 8.81 | 0.259 | 0.188 | ||
| Waist-to-hip ratio | 0.93 ± 0.06 | 0.93 ± 0.06 | 0.96 ± 0.04 | 0.041 | 0.041 | ||
| Total cholesterol (mmol/l) | 5.29 ± 1.29 | 5.48 ± 1.10 | 6.03 ± 0.87 | 0.038 | 0.130 | 0.056 | 0.198 |
| Triglycerides (mmol/l) | 2.04 ± 0.92 | 2.57 ± 1.64 | 2.77 ± 1.24 | 0.047 | 0.587 | 0.008 | 0.847 |
| HDL cholesterol (mmol/l) | 1.25 ± 0.30 | 1.24 ± 0.42 | 1.04 ± 0.19 | 0.034 | 0.047 | 0.077 | 0.063 |
| LDL cholesterol (mmol/l) | 3.49 ± 0.94 | 3.58 ± 0.96 | 4.06 ± 1.07 | 0.044 | 0.098 | 0.033 | 0.088 |
| Fasting blood glucose (mmol/l) | 6.69 ± 2.41 | 6.64 ± 2.71 | 6.13 ± 2.47 | 0.446 | 0.501 | ||
| Insulin (μU/ml) | 20.47 ± 10.76 | 20.04 ± 9.67 | 19.23 ± 14.68 | 0.694 | 0.802 | ||
| HOMA-IR | 6.30 ± 4.71 | 5.84 ± 3.22 | 5.24 ± 4.50 | 0.389 | 0.639 | ||
| Normal IMT | 80 | 41 | 2 | 0.001 | 0.017 | ||
| Mean IMT (mm) | 0.75 ± 0.15 | 0.76 ± 0.18 | 0.95 ± 0.18 | 0.00007 | 0.0002 | ||
| Maximum IMT (mm) | 1.07 ± 0.69 | 1.23 ± 0.88 | 2.44 ± 1.17 | 0.00000005 | 0.000002 | ||
Data are means ± SD unless otherwise indicated.
↵*P, adjusted for waist-to-hip ratio, sex, age, and smoking. HOMA-IR, homeostasis model assessment for insulin resistance.