Systemic immune mediator concentrations in patients with and without diabetic foot ulcer
| Immune mediator | Patients with ulcer | Patients without ulcer | P |
|---|---|---|---|
| CRP (mg/l) | 11.7 (3.3; 38.2) | 2.4 (1.0; 5.0) | <0.0001 |
| Fibrinogen (g/l) | 5.5 ± 1.6 | 3.8 ± 0.9 | <0.0001 |
| IL-6 (pg/ml) | 12.4 (6.9; 30.3) | 3.8 (2.2; 5.2) | <0.0001 |
| MIF (ng/ml) | 7.7 (5.6; 11.9) | 4.3 (3.1; 6.6) | <0.0001 |
| IL-18 (pg/ml) | 118.3 (84.2; 179.0) | 122.7 (85.0; 172.0) | NS |
| IL-8 (pg/ml) | 11.4 (7.1; 18.3) | 10.0 (6.8; 15.9) | NS |
| MIP-1α (pg/ml) | 82.6 (54.6; 132.7) | 61.2 (44.1; 107.4) | 0.008 |
| MCP-1 (pg/ml) | 291.0 (202.2; 381.9) | 303.3 (213.8; 415.6) | NS |
| IP-10 (pg/ml) | 419.8 (309.9; 543.4) | 299.4 (216.9; 401.6) | <0.0001 |
| RANTES (ng/ml) | 76.9 ± 38.2 | 100.3 ± 44.7 | <0.0001 |
Data are means ± SD or medians (25th percentile; 75th percentile).