Table 1

Clinical and laboratory characteristics of Charcot, neuropathic + diabetic, and healthy subjects

Ch groupND groupH groupP*
A1C (%)8.2 ± 2.418.0 ± 1.825.1 ± 0.41,2<0.001
Disease duration (years)20 ± 1121 ± 10
Weight (kg)97 ± 161,284 ± 171,374 ± 42,3<0.001
Waist circumference (cm)115 ± 141,2106 ± 121,397 ± 52,3<0.001
Age (years)59 ± 9164 ± 10162 ± 60.013
Sex (male/female)39/1926/1363/40NS
Total cholesterol (mg/dl)178 ± 47182 ± 38182 ± 38NS
LDL cholesterol (mg/dl)105 ± 35103 ± 35103 ± 35NS
HDL cholesterol (mg/dl)43 ± 945 ± 1245 ± 12NS
Triglycerides (mg/dl)161 ± 981144 ± 672144 ± 671,2<0.001
Conduction velocity (m/s)32.2 ± 4.533.2 ± 4.2NS
Conduction amplitude (μV)1.2 ± 0.41.3 ± 0.4NS
NDS: 6-7-8-9-1010-13-17-13-67-8-12-11-3NS
ANS: 3-4-5-6-7-88-16-14-14-5-26-12-10-9-3-1NS
  • Data are means ± SD.

  • *Significance of difference for the correspondent row. If the P value is significant (<0.05), apex numbers locate the difference between corresponding row subgroups.

  • †Data regarding Neuropathy Disability Score (NDS) (16) and Autonomic Neuropathy Score (ANS) (17) are expressed as frequencies of patients belonging to each score (e.g., Charcot: NDS 7, 13 patients; ND: ANS 4, 12 patients).