Table 1

Baseline characteristics of participants with both IFG and IGT, defined by the ADA

ILSMetforminPlacebo
n850832846
Age (years)50 (42–59)51 (44–57)50 (44–58)
Female555 (65.3)528 (63.5)559 (66.1)
Race/ethnic group
    White456 (53.6)474 (57.0)458 (54.1)
    African American164 (19.3)183 (22.0)184 (21.7)
    Hispanic143 (16.8)125 (15.0)132 (15.6)
    American Indian36 (4.2)21 (2.5)31 (3.7)
    Asian American51 (6.0)29 (3.5)41 (4.8)
Systolic blood pressure (mmHg)122 (113–133)123 (113–134)122 (114–132)
Diastolic blood pressure (mmHg)79 (73–85)79 (72–85)78 (71–84)
Waist circumference (cm)104 (95–115)105 (96–114)105 (96–115)
BMI (kg/m2)33 (29–37)33 (29–37)33 (29–38)
Activity (MET/h per week)
    Leisure9.5 (3.7–20)10 (3.9–21)9.8 (4.1–21)
    Recreational62 (36–91)63 (38–91)62 (39–90)
Caloric intake (kcal)1,881 (1,463–2,573)1,902 (1,472–2,568)1,874 (1,443–2,474)
Fasting plasma glucose (mmol/l)5.9 (5.7–6.3)5.9 (5.7–6.3)5.9 (5.7–6.3)
2-h plasma glucose (mmol/l)9.1 (8.3–9.9)9.2 (8.4–10.0)9.1 (8.3–9.9)
Triglycerides (mmol/l)1.6 (1.1–2.3)1.6 (1.1–2.2)1.7 (1.2–2.4)
HDL cholesterol (mmol/l)1.1 (1.0–1.3)1.1 (1.0–1.3)1.1 (0.9–1.3)
Insulin secretion0.52 (0.35–0.74)0.51 (0.34–0.74)0.53 (0.34–0.78)
Insulin sensitivity0.04 (0.03–0.06)0.04 (0.03–0.06)0.04 (0.03–0.06)
  • Data are n (%) for categorical variables and median (25th–75th percentile) for continuous variables. Twenty Pacific Islanders were included in the Asian American group. Insulin secretion was estimated using the CIR ([100 × 30 min insulin]/[30 min glucose × {30 min glucose −70}]). Insulin sensitivity was estimated using 1/fasting insulin.