Table 2

Multivariable Cox regression analysis for fatal and nonfatal coronary heart disease, congestive heart failure, and stroke in 3,468 patients with hypertension

Coronary heart diseaseCongestive heart failureStroke
Number of events12999113
Smoking1.87 (1.20–2.91)2.14 (1.22–3.76)0.89 (0.49–1.62)NS
24-h systolic blood pressure1.44 (1.21–1.71)*1.45 (1.19–1.78)*1.73 (1.45–2.06)*
Diabetes1.15 (0.64–2.04)NS2.05 (1.19–3.53)2.19 (1.34–3.57)
Cholesterol1.20 (1.07–1.35)1.05 (0.86–1.26)NS1.07 (0.91–1.27)NS
Age1.07 (1.05–1.09)*1.11 (1.08–1.14)*1.07 (1.05–1.09)*
Male sex2.70 (1.85–3.94)*1.32 (0.84–2.07)NS2.03 (1.36–3.02)*
  • Data are hazard ratios and 95% CIs associated with smoking and diabetes (coded as 1 if yes and 0 if no), 1 SD higher blood pressure or total cholesterol level, 1 year of age, and male sex (men = 1 and women = 0); antihypertensive treatment and BMI are not significant.

  • *P ≤ 0.001;

  • P ≤ 0.01; NSP > 0.05.