Table 1

Clinical characteristics and survival data

No CKDCKDHemodialysisTotalP
Demographics
    n5263891281,043
    Age [mean ± SD (range)]63.85 ± 12.76 (27–96)67.32 ± 11.91 (35–97)61.24 ± 11.5 (30–84)64.82 ± 12.4 (27–97)<0.001
    Sex (% male)65.852.252.359.1<0.001
Race0.066
    African American7.65.18.66.80.24
    Hispanic78.776.381.378.10.46
    Caucasian13.718.510.215.10.033
Comorbidities
    Coronary heart disease31.446.044.538.4<0.001
    Hypertension38.456.667.248.7<0.001
    Stroke15.017.013.315.50.5
    Coronary heart failure12.926.536.720.9<0.001
Diabetes medication
    Insulin45.855.360.951.2<0.001
    Oral agents41.329.620.334.3<0.001
    Diet controlled8.07.510.98.10.45
Surgery
    Coronary bypass7.613.420.311.3<0.001
    Lower-extremity bypass17.317.022.717.80.31
    History of amputation44.349.653.947.5<0.001
    Bilateral amputation24.730.136.728.20.015
Amputation by level
    Foot53.840.428.945.7<0.001
    Below knee27.035.743.832.3<0.001
    Above knee19.223.927.322.0<0.001
Percent survival after amputation
    1 year85.676.650.877.9<0.001
    2 years77.067.142.269.0<0.001
    3 years73.256.328.961.5<0.001
    4 years66.048.620.353.9<0.001
    5 years60.340.917.247.7<0.001
    6 years53.834.414.841.8<0.001
    7 years47.127.812.535.7<0.001
    8 years43.521.910.231.4<0.001
    9 years36.719.810.227.1<0.001
    10 years32.917.09.424.1<0.001