Change in wtSDS and lung function over the preceding year by glycemic groups
Change in* | Cystic fibrosis–specific OGTT cutoff | WHO categories based on BG120 | Cystic fibrosis–specific CGM-based cutoff | ||||||
---|---|---|---|---|---|---|---|---|---|
BGmax ≥8.2 mmol/l | BGmax <8.2 mmol/l | P | IGT: 7.8–11 mmol/l | NGT: <7.8 mmol/l | P | CGM >7.8 mmol/l ≥4.5% | CGM >7.8 mmol/l <4.5% | P | |
n (%) | 21/31 (68)† | 10/31 (32) | 13/31 (42)† | 18/31 (58) | 15/23 (65)† | 8/23 (35) | |||
wtSDS | −0.3 ± 0.4 | 0.0 ± 0.4 | 0.04 | −0.2 ± 0.4 | −0.2 ± 0.4 | 0.94 | −0.3 ± 0.4 | 0.1 ± 0.2 | 0.01 |
%FEV1 | −6 ± 7 | −4 ± 11 | 0.48 | −6 ± 7 | −5 ± 9 | 0.83 | −6 ± 7 | −2 ± 11 | 0.31 |
%FVC | −4 ± 7 | 0.5 ± 10 | 0.21 | −5 ± 6 | −1 ± 9 | 0.21 | −4 ± 7 | 1 ± 10 | 0.13 |
Data are means ± SD unless otherwise indicated. Change in weight and lung function in the preceding 12 months in 31 patients with cystic fibrosis, excluding the 2 patients with BG120 min ≥11.1 mmol/l (diabetic by WHO criteria) are shown. Groups are compared according to three different glycemic cutoffs.
↵*Over the preceding year.
↵†Excluding 2 patients (BG120 min >11.1 mmol/l).