Table 1

Time-specific primary outcomes by treatment group

CC groupACM + HT groupDiffCC-ACMP
n7364
A1C (%)
    Baseline9.4 ± 1.49.6 ± 1.6−0.2 (−0.7 to 0.3)0.53
    3 months8.7 ± 1.27.9 ± 1.20.7 (0.3 to 1.2)<0.001
    6 months8.6 ± 1.37.9 ± 1.20.7 (0.3 to 1.2)<0.001
Weight (lb)
    Baseline223.5 ± 47.9226.6 ± 45.4−3.1 (−18.9 to 12.7)0.70
    3 months222.0 ± 49.6225.5 ± 44.5−3.5 (−19.5 to 12.5)0.67
    6 months223.9 ± 48.6229.5 ± 47.6−5.7 (−21.9 to 10.6)0.49
Systolic blood pressure (mmHg)
    Baseline142.3 ± 19.0144.8 ± 21.7−2.6 (−9.5 to 4.3)0.46
    3 months137.1 ± 21.4135.9 ± 23.31.2 (−6.2 to 8.7)0.74
    6 months133.0 ± 19.0132.0 ± 24.31.0 (−6.2 to 8.2)0.79
Diastolic blood pressure (mmHg)
    Baseline80.5 ± 10.179.9 ± 13.30.6 (−3.4 to 4.5)0.78
    3 months76.6 ± 12.975.4 ± 12.01.3 (−2.9 to 5.4)0.55
    6 months75.9 ± 13.272.4 ± 14.63.5 (−1.1 to 8.2)0.13
Cholesterol (mg/dl)
    Baseline175.6 ± 43.5177.3 ± 54.2−1.7 (−18.2 to 14.8)0.84
    3 months160.8 ± 37.5149.8 ± 37.211.0 (−1.7 to 23.6)0.09
    6 months159.1 ± 37.2148.2 ± 40.211.0 (−2.0 to 24.0)0.10
HDL (mg/dl)
    Baseline38.4 ± 13.038.4 ± 13.50.0 (−4.5 to 4.5)0.99
    3 months36.2 ± 11.035.0 ± 10.71.3 (−2.4 to 4.9)0.50
    6 months36.4 ± 13.635.1 ± 11.31.3 (−3.0 to 5.5)0.55
LDL (mg/dl)†
    Baseline101.8 ± 32.098.8 ± 36.33.0 (−8.9 to 15.0)0.62
    3 months92.3 ± 32.286.3 ± 27.76.0 (−4.6 to 16.6)0.27
    6 months91.2 ± 30.682.3 ± 27.98.9 (−1.6 to 19.3)0.10
Triglycerides (mg/dl)
    Baseline194.1 ± 160.4191.3 ± 133.32.7 (−47.5 to 53.0)0.92
    3 months170.0 ± 133.6149.9 ± 114.120.1 (−22.3 to 62.5)0.35
    6 months170.7 ± 115.9152.4 ± 99.718.3 (−18.0 to 54.6)0.32
  • Data are means ± SD and mean differences (CC − ACM + HT) with 95% CIs for these differences at each time point. Corresponding P values are also shown. A positive difference (DiffCC-ACM) indicates that the mean for that outcome at that time point is lower in the ACM + HT group than in the CC group. *Because measurements are rounded to one decimal place for reporting purposes, the rounded difference scores may differ slightly from the differences of the rounded means.

  • †CC group: n = 69; ACM + HT group: n = 59.