Table 1

Patients at target

Group careControl subjectsAll patients*
Baseline4 yearsP (baseline vs. 4 years)Ba90 baseline4 yearsP (baseline vs. 4 years)Odds ratio (95% CI) of being at target for case versus control subjectsP
A1C ≤7.0% (percent of available data)150/420 (35.7%)135/315 (42.9)P < 0.001116/375 (30.9)10/270 (3.7)P < 0.00129.4 (14.2–60.8)P < 0.001
A1C ≤6.5% (percent of available data)99/420 (23.6)58/315 (18.4)NS69/375 (18.4)0/270 (0)P < 0.00182.08 (11.1–616.5)P < 0.001
Systolic blood pressure111/411 (27)113/295 (38.3)P < 0.002117/394 (29.7)84/266 (31.6)NS1.4 (0.9–1.9)NS
Diastolic blood pressure 80 mmHg236/411 (57.4)212/295 (71.9)P < 0.001255/394 (64.7)185/266 (69.5)NS1.2 (0.8–1.82)NS
Systolic blood pressure ≤130 and diastolic blood pressure ≤80 mmHg93/411 (22.6)105/295 (35.6)P < 0.001101/394 (25.6)74/266 (27.8)NS1.5 (1.02–2.1)P < 0.05
Total cholesterol ≤4.0 mmol/l (175 mg/dl)74/421 (17.6)107/308 (34.7)P < 0.00177/394 (19.5)37/264 (14.0)NS4.0 (2.5–6.4)P < 0.001
Triglyceride ≤1.7 mmol/l (150 mg/dl)251/421 (59.6)226/309 (73.1)P < 0.001212/394 (53.8)145/264 (54.9)NS2.3 (1.5–3.4)P < 0.001
LDL cholesterol ≤2.58 mmol/l (100 mg/dl)81/414 (19.6)115/305 (37.7)P < 0.00192/385 (23.9)53/262 (20.2)NS2.9 (1.9–4.4)P < 0.001
Patients at target for all variables§10/418 (2.4)15/308 (4.9)P < 0.0510/393 (2.5)1/270 (0.4)NS14.5P < 0.01
  • Data are n (%), unless otherwise indicated.

  • *Odds ratios have been estimated by a logistic model, where being at target at 4 years was considered as the dependent variable and belonging to the group of case or control subjects, age, sex, duration of diabetes, familiarity, and situation at baseline were the independent variables.

  • †McNemar test for paired samples.

  • ‡Friedwald formula: LDL cholesterol = total cholesterol − HDL cholesterol − triglycerides/5 (only patients with triglycerides <4.5 mmol/l included).

  • §A1C ≤7.0% + systolic blood pressure ≤130 mmHg + diastolic blood pressure ≤80 mmHg + LDL cholesterol ≤2.58 mmol/l (100 mg/dl).