Baseline characteristics
| Total | NOD (−) | NOD (+) | |
|---|---|---|---|
| n | 2,685 | 2,588 | 97 |
| Candesartan* | 1,343 (50.0) | 1,305 (50.4) | 38 (39.2) |
| Prior antihypertensive treatment | 1,767 (65.8) | 1,702 (65.8) | 65 (67.0) |
| Age (years) | 63.7 ± 11.1 | 63.7 ± 11.2 | 64.9 ± 10.0 |
| Male sex* | 1,471 (54.8) | 1,406 (54.3) | 65 (67.0) |
| BMI (kg/m2)* | 24.8 ± 3.6 | 24.1 ± 3.5 | 25.2 ± 3.4 |
| SBP (mmHg) | 165.0 ± 14.8 | 165.0 ± 14.8 | 165.7 ± 16.1 |
| DBP (mmHg)* | 94.3 ± 11.3 | 94.4 ± 11.3 | 90.5 ± 11.7 |
| Pulse pressure (mmHg)* | 70.8 ± 15.8 | 70.6 ± 15.7 | 75.2 ± 18.4 |
| Heart rate (beats/min) | 71.4 ± 10.9 | 71.4 ± 10.9 | 71.2 ± 9.5 |
| Hyperlipidemia | 1,178 (43.9) | 1,136 (43.9) | 42 (43.3) |
| Smoking | |||
| Never | 1,825 (68.0) | 1,766 (68.2) | 59 (60.8) |
| Ever | 273 (10.2) | 261 (10.1) | 12 (12.4) |
| Current | 587 (21.9) | 561 (21.7) | 26 (26.8) |
| Cerebrovascular disease† | 344 (12.8) | 330 (12.8) | 14 (14.4) |
| LVH* | 1,139 (42.4) | 1,088 (42.0) | 51 (52.6) |
| Ischemic heart disease | 393 (14.6) | 381 (14.7) | 12 (12.3) |
| Proteinuria | 548 (20.4) | 530 (20.5) | 18 (18.6) |
| Renal dysfunction | 205 (7.6) | 196 (7.6) | 9 (9.3) |
| Peripheral vascular disease | 37 (1.4) | 35 (1.4) | 2 (2.1) |