Table 2

Predictors of new-onset diabetes by multiple Cox regression analysis

Variables, unit of increaseHR (95% CI)P value
Pulse pressure, per 1 SD increase1.44 (1.15−1.79)0.001
Prior antihypertensive treatment, yes0.97 (0.61−1.54)0.901
Allocated drug, candesartan0.64 (0.42−0.97)0.037
Sex, male1.77 (1.07−2.92)0.026
Age, per 10 years1.09 (0.87−1.36)0.460
BMI, per 1 kg/m2 increase1.11 (1.06−1.17)<0.001
Heart rate, per 1 SD increase1.01 (0.82−1.23)0.960
Hyperlipidemia, yes1.04 (0.68−1.57)0.867
Smoking
    Ever1.03 (0.52−2.04)0.942
    Current1.22 (0.72−2.06)0.458
Cerebrovascular disease, yes1.48 (0.80−2.75)0.214
LVH, yes1.75 (1.13−2.72)0.013
Ischemic heart disease, yes0.91 (0.47−1.76)0.777
Renal damage, yes*1.10 (0.68−1.79)0.694
Peripheral vascular disease, yes1.49 (0.36−6.16)0.581
Additional use of diuretics, yes2.10 (1.25−3.52)0.005
Additional use of β-blockers, yes0.70 (0.40−1.24)0.226
Additional use of α-blockers, yes0.63 (0.32−1.24)0.185
  • Data are HR (95% CI) and are adjusted for each variable.

  • *Renal damage, proteinuria, and renal dysfunction.