Table 1

Baseline characteristics of the 165 normoalbuminuric type 1 diabetic patients who had their u-LFABP measured in 1990 or later, divided into groups according to their later development of microalbuminuria or macroalbuminuria or persistent normoalbuminuria

Persistent normoalbuminuriaOnly microalbuminuriaMacroalbuminuriaProgressorsP value*
n (male/female)62/6422/96/228/110.05
Age (years)37 ± 1241.7 ± 2.443 ± 941 ± 150.18
Diabetes duration (years)8.6 ± 3.48.4 ± 1.812.1 ± 4.59.0 ± 2.80.05
Systolic blood pressure (mmHg)122 ± 15128 ± 16138 ± 20130 ± 170.02
Diastolic blood pressure (mmHg)77 ± 879 ± 986 ± 1481 ± 100.01
UAER (mg/24 h)8 (7–9)11 (8–14)12 (7–20)11 (9–14)0.02
A1C (%)8.2 ± 1.18.6 ± 1.79.1 ± 0.98.7 ± 1.60.02
Serum creatinine (μmol/l)72 ± 1169 ± 1270 ± 1369 ± 120.48
u-LFABP/creatinine [(pg/ml)/(mg/dl)]9.6 (7.8–11.8)13.4 (8.4–21.3)12.6 (8.4–21)13.2 (8.8–19.9)0.35
  • Data are means ± SD or geometric means (95% CI). The microalbuminuria group does not include patients who later developed macroalbuminuria. Progressors include those who progressed to microalbuminuria and macroalbuminuria.

  • *Overall difference between normoalbuminuric, microalbuminuric, and macroalbuminuric groups compared by ANOVA.