Table 3

Multivariable analysis for prediction of hard cardiac events in all patients

No cardiac eventsCardiac eventsUnivariate modelMultivariate model
HR (95% CI)P valueHR (95% CI)P value
Diabetes133 (7)7 (26)3.5 (1.5–8.2)<0.001
Hypertension1,097 (58)21 (68)1.5 (0.7–3.2)0.3
Hypercholesterolemia973 (51)20 (65)1.6 (0.8–3.3)0.21
Smoking661 (35)10 (32)0.9 (0.4–1.8)0.68
Family history622 (33)7 (23)0.6 (0.2–1.3)0.2
Age58.5 ± 10.966.2 ± 8.41.1 (1–1.1)<0.0011.05 (1.02–1.09)0.006
Male sex1,284 (68)24 (77)1.5 (0.7–3.6)0.32
Atypical chest pain736 (39)9 (29)0.7 (0.3–1.5)0.34
Dyspnea57 (3)2 (6)1.9 (0.5–8)0.38
Atherosclerotic burden score3.0 ± 3.26.6 ± 4.31.3 (1.2–1.4)<0.0011.2 (1.1–1.3)<0.001
Coronary obstruction score0.9 ± 0.91.7 ± 0.92.5 (1.7–3.8)<0.001
Calcium score1.1 ± 1.02.2 ± 2.12.5 (1.6–3.8)<0.001
  • Data are means ± SD or n (%) unless otherwise indicated. The HR for the calcium score is calculated for a 10-fold increase.