Table 2

Early effects of RYGB and short-term diet restriction on body weight and fasting metabolic parameters

Before RYGBAfter RYGBBefore dietAfter diet
Weight (kg)153.2 ± 32.2151.8 ± 33.1127.0 ± 36.5124.2 ± 36.5*
BMI (kg/m2)51.9 ± 6.051.4 ± 6.644.2 ± 9.943.2 ± 10.0*
Glucose (mmol/l)6.4 ± 1.56.0 ± 1.86.8 ± 1.85.4 ± 1.1*
Insulin (pmol/l)236 ± 159155 ± 102*220 ± 196178 ± 217
HOMA-IR5.0 ± 3.13.3 ± 2.1*4.8 ± 4.13.6 ± 4.1*
GLP-1 (pg/ml)34.9 ± 32.436.5 ± 32.639.4 ± 14.939.3 ± 32.8
GIP (pg/ml)58.0 ± 31.642.4 ± 21.153.3 ± 29.033.7 ± 25.5
Leptin (ng/ml)72.4 ± 15.349.5 ± 15.1*61.1 ± 30.638.0 ± 21.9
Adiponectin (μg/ml)7.3 ± 3.06.4 ± 2.04.5 ± 2.64.7 ± 2.6
Acylated ghrelin (pg/ml)68.2 ± 33.648.5 ± 26.9*34.7 ± 23.526.1 ± 20.2
Total ghrelin (pg/ml)585 ± 272414 ± 107623 ± 205559 ± 268
  • Data are means ± SD.

  • *P < 0.05 compared with baseline within each group (RYGB or Diet).