Table 3

Metabolic responses to a mixed-meal before and after RYGB and diet

Before RYGBAfter RYGBBefore dietAfter diet
Glucose AUC (mmol · l−1 · min−1)1,829 ± 5101,714 ± 5681,966 ± 6411,637 ± 297
Peak glucose (mmol/l)8.4 ± 2.17.9 ± 2.59.4 ± 2.68.2 ± 1.5
Insulin AUC (mmol · l−1 · min−1)113 ± 6765 ± 33*85 ± 5965 ± 56*
Peak insulin (pmol/l)742 ± 347485 ± 307*532 ± 287406 ± 307*
GLP-1 AUC (pg · l−1 · min−1)9.2 ± 8.412.2 ± 5.5*10.2 ± 5.911.6 ± 6.4
Peak GLP-1 (pg/ml)45.2 ± 37.384.8 ± 33.0*58.8 ± 43.257.2 ± 28.4
GIP AUC (pg · l−1 · min−1)28.7 ± 12.323.5 ± 8.629.5 ± 13.530.1 ± 13.8
Peak GIP (pg/ml)227 ± 115193 ± 111235 ± 128228 ± 105
Ghrelin AUC (pg · l−1 · min−1)145 ± 53112 ± 36*162 ± 58142 ± 52
Nadir ghrelin (pg/ml)456 ± 165341 ± 84*543 ± 217393 ± 201
  • Data are means ± SD.

  • *P < 0.05 compared with baseline within each group (RYGB and diet).