Table 1

Mean cognitive relative scores* in adulthood and childhood, and change in relative scores from childhood to adulthood† in diabetic subjects with and without early‡ SH

Cognitive domainDiabetes with early SHDiabetes without early SHDifference§95% CIP
Relative score95% CIRelative score95% CI
    Motor speed0.1−0.60.8−0.3−−
    Psychomotor efficiency−1.1−2.0−0.30.1−0.40.7−1.3−2.3−0.20.02
    Problem solving−2.2−3.0−1.50.0−0.60.5−2.2−3.2−1.2<0.001
    Spatial function−1.0−2.00.1−0.1−0.80.6−0.9−
    Verbal function−1.7−2.6−0.8−0.2−0.80.4−1.5−2.6−0.40.01
    Motor speed0.1−0.70.9−0.3−−
    Psychomotor efficiency−0.8−−0.30.7−1.0−1.9−0.10.04
    Problem solving−0.3−−0.40.3−0.3−
    Spatial function−0.2−1.10.7−0.1−0.70.5−0.1−
    Verbal function−1.0−1.7−0.30.0−0.50.4−1.0−1.8−0.10.03
Change from childhood to adulthood
    Motor speed0.0−−−
    Psychomotor efficiency−0.4−1.00.3−0.1−0.50.4−0.3−
    Problem solving−1.9−2.7−1.20.0−0.60.5−1.9−2.9−0.9<0.001
    Spatial function−0.8−−0.60.5−0.8−
    Verbal function−0.7−1.50.1−0.2−0.70.3−0.5−
  • *Difference in test scores between diabetic subjects and control subjects with the SD among control subjects as the unit of measure.

  • †Computed as (relative score at follow-up–relative score at baseline).

  • ‡Defined as first SH ≤10 years of age.

  • §Difference in relative score between diabetic subjects with and without early SH.

  • P value for the difference between diabetic subjects with and without early SH.

  • n = 8 (diabetic–matched control subject) pairs.