Table 1

Unadjusted and adjusted mean CD36 mRNA/protein and Pearson product moment correlations (r)

CD36 mRNA (log r.u.)CD36 protein (log r.u.)
Type 2 diabetesNondiabetic control subjectsType 2 diabetesNondiabetic control subjects
n33273327
Unadjusted mean0.23 ± 0.020.16 ± 0.020.28 ± 0.02§0.18 ± 0.02
Model 10.21 ± 0.020.17 ± 0.020.27 ± 0.01*0.21 ± 0.02
Model 20.20 ± 0.020.18 ± 0.020.26 ± 0.010.20 ± 0.01
CD36 mRNA (log r.u.)NANAr = 0.64r = 0.63
PPAR-γ mRNA (log r.u.)r = 0.73r = 0.72r = 0.33#r = 0.46*
hsCRP (log mg/dl)r = 0.55r = 0.21r = 0.45r = 0.43*
hsIL-6 (log pg/ml)r = 0.40*r = 0.49r = 0.64r = 0.49
TNF-α (log pg/ml)r = −0.20r = 0.09r = −0.28r = −0.02
Adiponectin (log μg/ml)r = −0.61r = −0.67r = −0.60r = −0.56
BMI (kg/m2)r = 0.20r = 0.03r = 0.09r = 0.17
HOMA-IR (log r.u.)r = 0.18r = 0.03r = 0.12r = −0.07
QUICKI (log r.u.)r = −0.20r = 0.05r = −0.16r = 0.19
  • Data are least squares means ± SEM unless otherwise indicated. The P value is from a t test of equality of the means. Model 1 adjusts for hypertension (HTN), hsIL-6, PPAR, adiponectin, and QUICKI. Model 2 adjusts for hsIL-6, adiponectin, and QUICKI.

  • *P < 0.05,

  • P < 0.01,

  • P < 0.001,

  • §P < 0.0001,

  • #P = 0.08. HOMA-IR, homeostasis model assessment–insulin resistance; QUICKI, quantitative insulin sensitivity check index; r.u., relative units.