Table 2

Predictors of conversion to type 2 diabetes by multiple logistic regression analysis

OR (95% CI)P
Model 1*
    Age (× 1 SD)1.09 (0.87–1.38)0.449
    Female vs. male0.93 (0.52–1.69)0.824
    Family history of diabetes (yes vs. no)1.25 (0.79–1.96)0.340
    BMI (× 1 SD)1.33 (0.87–2.05)0.187
    Waist circumference (× 1 SD)0.74 (0.47–1.18)0.206
    Fasting glucose concentration (× 1 SD)1.60 (1.24–2.06)<0.001
    2-h glucose concentration (× 1 SD)1.95 (1.48–2.57)<0.001
    Disposition index (× 1 SD)0.68 (0.54–0.85)0.001
    Glucose effectiveness (× 1 SD)0.61 (0.47–0.80)<0.001
Model 2
    Age (× 1 SD)1.10 (0.87–1.39)0.422
    Female vs. male0.91 (0.50–1.65)0.754
    Family history of diabetes (yes vs. no)1.25 (0.80–1.96)0.328
    BMI (× 1 SD)1.39 (0.90–2.14)0.137
    Waist circumference (× 1 SD)0.72 (0.45–1.17)0.190
    Fasting glucose concentration (× 1 SD)1.54 (1.18–2.00)0.001
    2-h glucose concentration (× 1 SD)1.91 (1.44–2.53)<0.001
    Insulin sensitivity index (× 1 SD)0.61 (0.44–0.86)0.004
    Acute insulin response (× 1 SD)0.73 (0.55–0.95)0.022
    Glucose effectiveness (× 1 SD)0.67 (0.50–0.88)0.005
  • ORs expressed for binary traits or per 1 SD unit change for continuous traits.

  • *Results in Model 1 adjusted also for race/ethnicity (P = 0.494) and research center (P = 0.006);

  • †log-transformed variables;

  • ‡results in Model 2 also adjusted for race/ethnicity (P = 0.446) and research center (P = 0.006).