Table 1

Cardiac events in risk groups according to various risk stratification schemes

Low riskIntermediate riskHigh riskIntermediate/high riskP*HR (95% CI)
Framingham score
    n283542298840
    Primary cardiac events4 (1.4)14 (2.6)14 (4.7)28 (3.3)0.092.4 (0.84–6.85)
    Secondary cardiac events5 (1.8)15 (2.8)15 (5.0)30 (3.6)0.122.07 (0.80–5.34)
    Revascularizations9 (3.2)40 (7.4)26 (8.7)66 (7.9)0.0062.57 (1.28–5.16)
UKPDS risk engine
    n515447142589
    Primary cardiac events6 (1.2)11 (2.5)14 (9.9)25 (4.2)0.0023.65 (1.50–8.90)
    Secondary cardiac events12 (2.3)16 (3.6)7 (4.9)23 (3.9)0.131.70 (0.84–3.41)
    Revascularizations18 (3.5)39 (8.7)17 (12.0)56 (9.5)0.00012.80 (1.65–4.77)
ALFEDIAM/SFC criteria
    n410713
    Primary cardiac events8 (2.0)24 (3.4)0.191.71 (0.77–3.80)
    Secondary cardiac events5 (1.2)30 (4.2)0.013.46 (1.34–8.91)
    Revascularizations22 (5.4)53 (7.4)0.211.38 (0.84–2.26)
Metabolic syndromeNoYes
    n319804
    Primary cardiac events8 (2.5)24 (3.0)0.671.19 (0.54–2.65)
    Secondary cardiac events8 (2.5)27 (3.4)0.461.35 (0.61–2.96)
    Revascularizations21 (6.6)54 (6.7)0.91.03 (0.62–1.71)
  • Data are n (%), unless otherwise indicated.

  • *P values are shown for low risk versus intermediate/high risk for Framingham and UKPDS; low risk versus high risk for ALFEDIAM/SFC; no versus yes for metabolic syndrome.