Table 2

Pre- and postprandial glucose control with prandial insulin boluses calculated by women according to insulin/carbohydrate ratio and fingerstick glucose values

VariableEarly pregnancyLate pregnancyP value
Before and after 80-g carbohydrate evening meal
Plasma glucose at start (1400 h), mg/dL118.8 (95.4–149.4)102.6 (75.6–140.4)0.5
Plasma glucose pre-evening meal (1800 h), mg/dL88.2 (68.4–127.8)73.8 (64.8–82.8)0.14
Median postprandial plasma glucose (1800–2300 h), mg/dL104.4 (100.8–136.8)108 (82.8–135)0.20
SD plasma glucose25.2 (14.4–32.4)19.8 (18–25.2)0.24
% Time in target (63–140 mg/dL)68 (61–97)77 (58–93)0.51
% Time hypoglycemic <63 mg/dL0 (0–8)3 (0–18)0.46
% Time hypoglycemic <50 mg/dL0 (0–0)0 (0–0)0.65
% Time hyperglycemic >140 mg/dL13 (0–39)5 (0–41)0.24
% Time hyperglycemic >180 mg/dL0 (0–2)0 (0–0)0.18
Blood glucose index
 Low1.2 (0.1–2.0)1.2 (0.5–6.3)0.44
 High0.7 (0.0–2.2)0.3 (0.0–1.7)0.17
Mean insulin infusion, units/kg0.5 (0.3–0.6)0.6 (0.2–0.9)0.96
SD insulin infusion rate0.5 (0.4–0.7)0.6 (0.4–0.9)0.72
Before and after 60-g carbohydrate breakfast
Fasting plasma glucose (0700 h)109.8 (95.4–126)118.8 (102.6–133.2)0.14
Median postprandial plasma glucose (0700–1200 h), mg/dL117 (100.8–154.8)126 (109.8–140.4)0.72
SD plasma glucose32.4 (18.0–41.4)34.2 (21.6–48.6)0.80
% Time in target (63–140 mg/dL)59 (40–74)47 (39–77)0.88
% Time hypoglycemic <63 mg/dL1 (0–23)1 (0–18)1.0
% Time hypoglycemic <50 mg/dL0 (0–0)0 (0–1)0.18
% Time hyperglycemic >140 mg/dL28 (20–58)44 (10–55)0.86
% Time hyperglycemic >180 mg/dL0 (0–25)3 (0–24)0.83
Blood glucose index
 Low1.2 (0.2–5.5)1.5 (0.1–3.7)0.80
 High1.2 (0.8–5.6)2.1 (0.4–4.3)0.96
Mean insulin infusion, units/kg0.3 (0.2–0.9)0.5 (0.3–1.0)0.24
SD insulin infusion rate0.7 (0.2–1.0)0.5 (0.1–1.3)0.88
  • Values are given as median (interquartile range).