Table 2

Characteristics of preadolescents with type 1 diabetes according to glycemic control

ParametersOptimal (HbA1c <8.0%)Suboptimal (HbA1c ≥8.0%)P
n1110
Age (years)8.5 ± 0.38.1 ± 0.40.438
Sex (% female)72.740.00.287
Diabetes duration4.8 ± 0.63.8 ± 0.40.190
Insulin regimen (% CSII)63.6300.72
Insulin dose (units ⋅ kg−1 ⋅ day−1)0.77 ± 0.170.88 ± 0.190.670
BMI (kg/m2)17.5 ± 0.517.6 ± 1.20.937
BMI z score0.56 ± 0.220.47 ± 0.320.816
Mean SBP (mmHg)100.3 ± 1.795.6 ± 3.20.198
Mean DBP (mmHg)57.4 ± 1.959.9 ± 1.50.321
FPG (mg/dL)169.9 ± 11.3176.3 ± 12.70.709
2-week MBG (mg/dL)174.8 ± 8.1231.7 ± 12.80.001*
2-week blood glucose SD (mg/dL)43.1 ± 3.666.6 ± 8.10.013
Hypoglycemia rate/week (blood glucose <60 mg/dL)1.7 ± 0.31.8 ± 0.30.817
HbA1c (%)7.4 ± 0.18.7 ± 0.30.0004
Triglycerides (mg/dL)58.0 ± 5.666.2 ± 14.70.595
Cholesterol (mg/dL)163.6 ± 6.8176.1 ± 9.40.288
LDL cholesterol (mg/dL)103.0 ± 7.9112.4 ± 9.60.455
HDL cholesterol (mg/dL)49.2 ± 2.950.4 ± 4.90.831
Cholesterol–to–HDL cholesterol3.5 ± 0.33.8 ± 0.40.551
hs-CRP (mg/L)2.5 ± 0.71.3 ± 0.400.163
Homocysteine (μmol/L)4.4 ± 0.304.2 ± 0.400.690
RBC folate (ng/mL)349.5 ± 11.8353.3 ± 22.30.878
Fibrinogen (mg/dL)333.1 ± 18.4294.9 ± 10.90.097
FMD%5.5 ± 0.99.1 ± 1.10.019
c-IMT (mm)0.48 ± 0.020.46 ± 0.020.497
  • Data are means ± SE.

  • MBG, mean blood glucose.

  • *P < 0.01;

  • P < 0.02;

  • P < 0.001.