Table 2

Independent associations with all-cause mortality and cumulative incidence of cardiovascular mortality in individuals with type 2 diabetes

All-cause mortality
Baseline parameterHazard ratioP95% CI
24-h urinary sodium excretion (per 100 mmol/day)0.720.0170.55–0.94
Age (per decade)1.05<0.0011.03–1.07
Male sex (yes/no)1.510.0131.09–2.09
Pre-existing CVD (yes/no)1.850.0011.30–2.64
eGFR (per 10 mL/min/1.73 m2)0.9880.0020.980–0.996
Atrial fibrillation (yes/no)1.97<0.0011.39–2.81
Log10 AER1.71<0.0011.38–2.12
Systolic blood pressure (mmHg)0.9860.0150.974–0.997
Diabetes duration (decades)1.020.0101.01–1.04
Cardiovascular mortality
Baseline parameterSub-hazard ratioP95% CI
24-h urinary sodium excretion (per 100 mmol/day)0.650.0260.44–0.95
Male sex (yes/no)1.930.0111.17–3.20
Pre-existing CVD (yes/no)1.880.0141.14–3.11
eGFR (per 10 mL/min/1.73 m2)0.9850.0010.98–0.99
Atrial fibrillation (yes/no)2.78<0.0011.71–4.53
Log10 AER1.76<0.0011.28–2.42
Systolic blood pressure (mmHg)0.97<0.0010.96–0.99
Diabetes duration (decades)1.05<0.0011.02–1.08
  • All-cause mortality: independent associations with all-cause mortality in individuals with type 2 diabetes in a multivariate Cox model. The model explained 52% of the variation in all-cause mortality (95% CI 0.42– 0.64) and was well specified (Harrell’s C: 0.79; PH test: P = 0.136; goodness-of-fit test: P ≥ 0.37). PH, proportional hazard. Cardiovascular mortality: independent associations with the cumulative incidence of cardiovascular mortality in individuals with type 2 diabetes in the Fine and Gray (proportional hazards) model after accounting for the competing risk of noncardiovascular death.