Table 3

Comparison of trajectories reaching similar final BMI to ascertain importance of accelerated adiposity gain

Cardiovascular risk factorComparison groups 1 and 2P valueComparison groups 3 and 4P value
β (95% CI)β (95% CI)
Boys
 HOMA-IR
  Model 11.2 (1.0–1.5)0.0631.3 (1.1–1.5)0.001
  Model 21.2 (1.0–1.5)0.0721.3 (1.1–1.5)0.001
 Insulin
  Model 11.2 (1.0–1.5)0.0901.3 (1.1–1.5)0.001
  Model 21.2 (1.0–1.5)0.0961.3 (1.1–1.5)0.001
Girls
 HOMA-IR
  Model 11.0 (0.8–1.3)0.841.1 (0.9–1.2)0.34
  Model 21.0 (0.8–1.3)0.831.0 (0.9–1.2)0.54
 Insulin
  Model 11.1 (0.8–1.3)0.761.1 (0.9–1.2)0.41
  Model 21.0 (0.8–1.3)0.751.1 (0.9–1.2)0.64
  • Model 1 adjusted for age, gestational age, ethnicity, diet, exercise, low family income, and current BMI. Model 2 also adjusted for birth weight.

  • Groups 1 (“stable high”) and 3 “falling to moderate” are referent groups. These referent groups are compared with rising trajectories that reach similar current BMI. The bold text indicates results associated with a P value < 0.05.