Table 2

ORs and 95% CI of PD according to baseline diabetes status and disease duration*

DiabetesDiabetes duration (years)
NoYesNone<10≥10P for trend
All Parkinson diagnoses since 1995
 All participants
  Number of PD patients1,3931721,3938866
  OR (95% CI)1.01.41 (1.20–1.66)1.01.11 (0.89–1.38)1.75 (1.36–2.25)<0.0001
 Excluding participants with stroke, heart disease, cancers, and poor/fair health
  Number of PD patients952799524030
  OR (95% CI)1.01.34 (1.06–1.69)1.01.00 (0.73–1.38)1.80 (1.25–2.60)0.008
Parkinson diagnoses between 1995 and 1999
 All participants
  Number of PD patients465524652523
  OR (95% CI)1.01.31 (0.97–1.75)1.00.97 (0.64–1.45)1.85 (1.21–2.83)0.02
 Excluding participants with stroke, heart disease, cancers, and poor/fair health
  Number of PD patients328273281212
  OR (95% CI)1.01.34 (0.90–2.00)1.00.87 (0.49–1.56)2.12 (1.18–3.78)0.05
Parkinson diagnosis after 2000
 All participants
  Number of PD patients9281209286343
  OR (95% CI)1.01.46 (1.20–1.77)1.01.18 (0.91–1.53)1.70 (1.25–2.31)0.001
 Excluding participants with stroke, heart disease, cancers, and poor/fair health
  Number of PD patients624526242818
  OR (95% CI)1.01.33 (1.00–1.78)1.01.07 (0.73–1.56)1.64 (1.02–2.63)0.06
  • *Adjusting for age, sex, race, education, smoking, coffee, BMI, and physical activity. The numbers of participants without PD for the overall analyses were 265,658 (no diabetes), 21,439 (diabetes), 14,280 (diabetes <10 years), and 6,255 (diabetes duration ≥10 years). For the analysis excluding stroke, heart disease, cancers, and poor/fair health, the numbers were 203,299, 11,393, 7,878, and 3,030, respectively.