Table 1

Patient characteristics according to baseline quartiles of pulse pressure

1st2nd3rd4thP valueAge-corrected P value
Patients (N)1,1451,0801,1371,147
Sex (% women)42505856<0.001<0.001
Age (years)33 ± 936 ± 1039 ± 1247 ± 12<0.001
Duration (years)17 ± 919 ± 1122 ± 1230 ± 12<0.001<0.001
Age at onset (years)16 ± 1117 ± 1117 ± 1117 ± 110.25<0.001
BMI (kg/m2)24.6 ± 3.724.8 ± 3.825.2 ± 3.525.5 ± 3.7<0.0010.025
HbA1c (%)8.5 ± 1.78.4 ± 1.58.4 ± 1.48.5 ± 1.50.160.022
Total cholesterol (mmol/L)4.9 ± 1.04.9 ± 1.04.9 ± 1.05.2 ± 1.1<0.001<0.001
HDL cholesterol (mmol/L)1.6 ± 0.51.6 ± 0.51.6 ± 0.61.6 ± 0.50.490.073
LDL cholesterol (mmol/L)3.0 ± 0.83.0 ± 1.13.0 ± 0.93.2 ± 0.9<0.0010.159
Triacylglycerol (mmol/L)1.02 (0.77–1.43)1.00 (0.75–1.41)1.04 (0.77–1.46)1.10 (0.81–1.58)0.03<0.001
Insulin dose (IU/kg)0.74 ± 0.260.72 ± 0.260.70 ± 0.250.66 ± 0.24<0.0010.005
SBP (mmHg)118 ± 10127 ± 10136 ± 11156 ± 16<0.001<0.001
DBP (mmHg)80 ± 980 ± 1079 ± 1079 ± 110.390.022
PP (mmHg)38 ± 548 ± 257 ± 376 ± 12<0.001<0.001
Mean arterial pressure (mmHg)80 ± 982 ± 1085 ± 1092 ± 11<0.001<0.001
History of CVD (%)46719<0.001<0.001
History of smoking (%)474547500.1090.241
Antihypertensive medication (%)24283862<0.001<0.001
eGFR (mL/min/1.73 m2)92 ± 3093 ± 3190 ± 3487 ± 34<0.001<0.001
Diabetic nephropathy (%)13152040<0.001<0.001
  • Values are expressed as means ± SD, percent, or median (interquartile range).

  • eGFR, estimated glomerular filtration rate.