Table 3

Cox regression analysis for an incident CVD event (coronary event, stroke, peripheral vascular event) and progression in renal status (defined as any increase in albuminuria level or progression to ESRD)

Incident CVD eventProgression in renal status
HR (95% CI)P valueHR (95% CI)P value
Age (years)1.06 (1.04–1.08)<0.0011.00 (0.99–1.02)0.81
Male sex1.11 (0.79–1.54)0.552.01 (1.47–2.76)<0.001
HbA1c (%)1.06 (0.95–1.18)0.321.41 (1.30–1.53)<0.001
Total cholesterol (mmol/L)1.26 (1.10–1.45)0.0011.19 (1.04–1.37)0.01
eGFR (mL/min/1.73 m2)0.99 (0.98–0.99)<0.0011.00 (0.99–1.01)0.88
History of smoking1.45 (1.20–1.59)0.0011.20 (0.92–1.41)0.15
Antihypertensive medication0.43 (0.31–0.71)<0.0010.58 (0.42–0.81)0.001
PP (per 10 mmHg)1.22 (1.10–1.34)<0.0011.00 (0.89–1.12)0.96
  • Variables are from baseline.

  • eGFR, estimated glomerular filtration rate; HR, hazard ratio.