Table 4

Cox regression analysis for an incident CVD event (coronary event, stroke, peripheral vascular event) in patients by albuminuria status at baseline

CVD event
NormoalbuminuriaMicroalbuminuriaMacroalbuminuria
HR (95% CI)P valueHR (95% CI)P valueHR (95% CI)P value
Age (years)1.08 (1.04–1.11)<0.0011.09 (1.05–1.14)<0.0011.04 (1.01–1.07)0.009
Male sex1.24 (0.67–2.28)0.491.12 (0.43–2.95)0.821.15 (0.67–1.98)0.68
HbA1c (%)1.14 (0.88–1.47)0.331.29 (0.95–1.76)0.111.04 (0.89–1.22)0.61
Total cholesterol (mmol/L)1.44 (1.05–1.98)0.020.92 (0.55–1.52)0.731.24 (1.02–1.52)0.03
eGFR (mL/min/1.73 m2)0.99 (0.97–1.01)0.231.01 (0.99–1.03)0.310.99 (0.98–1.00)0.046
History of smoking1.52 (1.10–1.74)0.021.26 (0.15–1.70)0.521.31 (0.84–1.59)0.17
Antihypertensive medication0.50 (0.27–0.95)0.030.69 (0.26–1.82)0.460.96 (0.23–4.10)0.96
PP (per 10 mmHg)1.31 (1.07–1.61)0.0091.41 (1.04–1.93)0.031.18 (1.03–1.38)0.02
  • Variables are from baseline.

  • eGFR, estimated glomerular filtration rate; HR, hazard ratio.