Table 1

Overall and age- and sex-specific incidence densities and relative hazards of malignant neoplasm of pancreas (ICD-9: 157) in diabetic and control groups

Variables*Control groupDiabetic groupCrude HR
(95% CI) in
association with
diabetic groupAdjusted HR
(95% CI) in
association with
diabetic group§
Patients (n)Events (n)Incidence density (per 10,000
patient-years)
(95% CI)Patients (n)Events (n)Incidence density (per 10,000
patient-years)
(95% CI)
Men
 Age (years)
  <4540,53770.26 (0.07–0.45)40,537140.54 (0.26–0.83)2.10 (0.85–5.81)1.92 (0.76–4.89)
  45–65141,8991201.28 (1.05–1.51)141,8992222.46 (2.14–2.78)1.93 (1.55–2.41)1.91 (1.52–2.39)
  >65113,1271932.66 (2.28–3.03)113,1292563.71 (3.25–4.16)1.40 (1.16–1.69)1.47 (1.21–1.77)
 Total295,5633201.88 (1.68–2.07)295,5664923.34 (3.08–3.60)1.62 (1.40–1.86)1.66 (1.44–1.91)
Women
 Age (years)
  <4529,08020.10 (−0.04 to 0.25)29,079100.54 (0.21–0.87)5.15 (1.13–23.50)4.46 (0.96–20.70)
  45–65154,911830.81 (0.63–0.98)154,9111421.43 (1.20–1.67)1.78 (1.36–2.34)1.80 (1.37–2.36)
  >65135,3172322.62 (2.28–2.95)135,3182743.23 (2.85–3.61)1.24 (1.04–1.47)1.26 (1.06–1.51)
 Total319,3083171.71 (1.54–1.89)319,3104262.58 (2.36–2.80)1.40 (1.21–1.62)1.43 (1.23–1.65)
Overall614,8716371.79 (1.66–1.92)615,5329182.94 (2.77–3.11)1.51 (1.36–1.67)1.54 (1.39–1.71)
  • Data are HR (95% CI) unless otherwise indicated.

  • *Inconsistency between total population and population summed for individual variable was a result of missing information.

  • †Based on the Poisson assumption.

  • ‡Based on Cox proportional hazards regression without adjustment.

  • §Based on Cox proportional hazards regression with adjustment for age, sex, and geographic area and urbanization status; status of hepatitis B, hepatitis C, cholecystitis, cholangitis, cholelithiasis, choledocholithiasis, cholecystectomy, gastric ulcer, and duodenal ulcer; and gastrectomy.