Table 1

Relationship between SBP and SNPs of NPR3 in patients from the DIABHYCAR study

SNPGenotypeP value codominant model*A1 carriersP value A1 dominant modelA2 carriersP value A2 dominant model
A1A1A1A2A2A2
rs6889608CCCTTTC carriersT carriers
n = 231n = 1,151n = 1,715n = 1,382n = 2,866
145.2 ± 12.3144.9 ± 13.0143.7 ± 13.40.034/0.012145.0 ± 12.90.010144.2 ± 13.30.26
rs1173773GGAGAAG carriersA carriers
n = 332n = 1,397n = 1,369n = 1,729n = 2,766
142.4 ± 13.2144.4 ± 13.5144.7 ± 12.90.018/0.019144.1 ± 13.50.16144.5 ± 13.20.005
rs2207915GGAGAAG carriersA carriers
n = 140n = 987n = 1,971n = 1,127n = 2,958
145.8 ± 13.9144.8 ± 13.5143.9 ± 13.00.08/0.024144.9 ± 13.60.035144.2 ± 13.20.17
  • Data are means ± SD.

  • */§ Upper P values correspond to ANOVA statistics: A1A1 vs. A1A2 vs. A2A2./lower P values correspond to simple regression analysis: 0, 1, or 2 minor alleles.

  • †A1 carriers vs. A2A2.

  • ‡A2 carriers vs. A1A1.