Table 2

Relationship between SBP and SNPs of NPR3 in Europid patients from the D2NG/SDG studies

SNPGenotypeP value codominant model*/†A1 carriersP value A1 dominant modelA2 carriersP value A2 dominant model§
A1A1A1A2A2A2
rs6889608CCCTTTC carriersT carriers
n = 116n = 685n = 1,160n = 801n = 2,230
135.5 ± 20.1139.0 ± 19.2138.4 ± 19.70.20/0.56138.5 ± 19.30.93138.6 ± 19.50.09
rs1173773GGAGAAG carriersA carriers
n = 234n = 864n = 860n = 1,098n = 2,190
140.0 ± 19.1138.9 ± 20.1137.6 ± 18.90.16/0.056139.1 ± 19.90.08138.2 ± 19.50.19
rs2207915GGAGAAG carriersA carriers
n = 91n = 659n = 1,271n = 750n = 2,440
137.0 ± 19.8140.4 ± 20.2137.4 ± 19.10.004/0.031140.0 ± 20.20.004138.4 ± 19.50.48
  • Data are means ± SD.

  • */†Upper P values correspond to ANOVA statistics: A1A1 vs. A1A2 vs. A2A2./lower P values correspond to simple regression analysis: 0, 1, or 2 minor alleles.

  • ‡A1 carriers vs. A2A2.

  • §A2 carriers vs. A1A1.