Table 1

Clinical and metabolic features of the VNDS population

VariableMaleFemaleAll
n (M/F)342167509
Age (years)58 [51–65]61 [55–66]59 [52–65]
BMI (kg/m2)28.7 [26.2–32.4]30.8 [27.4–34.5]29.4 [26.5–33.2]
Waist (cm)102 [94–112]97 [91–104]100 [93–108]
Fasting P-glucose (mmol/L)7 [6.2–8.0]7.3 [6.2–8.1]7.1 [6.2–8.0]
2-h P-glucose (mmol/L)13.7 [11.0–16.4]13.3 [10.2–16.3]13.5 [10.6–16.3]
HbA1c (%)6.7 [6.1–7.6]6.7 [6.2–7.4]6.7 [6.2–7.5]
Triglycerides (mmol/L)1.4 [1.0–2.1]1.3 [1.0–2.0]1.4 [1.0–2.0]
HDL cholesterol (mmol/L)1.1 [1.0–1.3]1.2 [1.0–1.4]1.1 [1.0–1.4]
Cholesterol (mmol/L)4.9 [4.2–5.5]5.1 [4.5–5.8]5.0 [4.3–5.6]
Systolic blood pressure (mmHg)134 [120–150]140 [130–150]138 [124–150]
Diastolic blood pressure (mmHg)82 [80–90]85 [80–90]84 [80–90]
Insulin sensitivity (μmol/min/m2 BSA)565 [314–834]546 [394–755]559 [351–800]
Insulinogenic index (mU/mmol)3.5 [2.0–5.8]4.6 [2.3–8.1]3.8 [2.0–6.7]
CIR120’ (mU × L/mmol2)0.4 [0.2–1.1]0.6 [0.2–1.4]0.5 [0.2–1.2]
eGFR (mL/min/1.73 m2)84.4 [74.7–96.3]74.9 [62.5–86.1]80.0 [70.3–93.4]
Urinary albumin/creatinine (mg/mmol)0.8 [0.4–3.1]0.6 [0.3–1.5]0.8 [0.4–2.5]
Serum creatinine (μmol/L)82 [74–90]69 [62–80]79 [68–88]
  • Data are presented as median [interquartile range].