Table 1

Characteristics of three groups of patients (n = 1,005) with morbid obesity presenting with normal glucose tolerance, impaired glucose tolerance, or type 2 diabetes

NGTIGTType 2 diabetes
n547248210
Age (years)37 ± 1141 ± 1147 ± 11
BMI (kg/m2)44.2 ± 7.435.7 ± 13.045.8 ± 10.3
Glucose (mg/dL)
 Fasting85 ± 8*101 ± 12†156 ± 55
 1-h139 ± 35*185 ± 40†246 ± 72
 2-h98 ± 22*148 ± 32†238 ± 61
Insulin (µU/mL)
 Fasting23.1 ± 15.7*30.5 ± 22.234.2 ± 27.8
 1-h141.5 ± 92.9158.9 ± 97.2134.7 ± 75.3
 2-h141.5 ± 92.9*144.7 ± 126.4161.2 ± 110.4
HOMA-IR4.8 ± 3.5*7.6 ± 5.5†11.8 ± 10.9
HbA1c (%)5.5 ± 0.5*5.8 ± 0.5†7.8 ± 1.7
  • Data are means ± SD. In between group differences were analyzed by Student unpaired t test. An α-level <0.05 was considered statistically significant. HOMA-IR, homeostasis model assessment of insulin resistance; IGT, impaired glucose tolerance; NGT, normal glucose tolerance.

  • *P < 0.001 normal glucose tolerance vs. type 2 diabetes.

  • P < 0.001 impaired glucose tolerance vs. type 2 diabetes.