Table 1

Study group characteristics

Control dendritic cellsImmunosuppressive dendritic cells
n37
Age (years)
 Mean30.3 ± 4.531.6 ± 13.3
 Median3027
 Range26–3519–57
Male sex [n (%)]2 (67)4 (57)
Race or ethnicity (self-reported) [n (%)]
 White3 (100)7 (100)
 Non-Hispanic3 (100)7 (100)
Type 1 diabetes autoantibodies [n (%)]
 00 (0)2 (29)
 12 (67)3 (43)
 21 (33)1 (14)
Years since diagnosis18.0 ± 3.015.0 ± 7.5
Years from diagnosis to first injection of dendritic cells
 Median1814
 Range14–185–26
Weight (kg)84.6 ± 12.587.0 ± 25.4
BMI28.2 ± 3.427.3 ± 6.4
Total white blood cells (per mm3) (×106/mL)8.3 ± 1.95.9 ± 1.6
Glycated HbA1c at baseline (%)8.73 ± 1.768.26 ± 2.22
C-peptide at baselineUndetectableUndetectable
Total insulin dose (units/kg)0.49 ± 0.200.32 ± 0.05
Received all four rounds of dendritic cell injections [n (%)]3 (100)7 (100)
  • Data are means ± SD, unless otherwise indicated. BMI is weight in kilograms divided by the square of height in meters.